Reactome | MAPK9 [cytosol]

MAPK9 [cytosol]

Stable Identifier

R-MMU-450355

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

Q9WTU6

Locations in the PathwayBrowser

Expand all

Immune System (Mus musculus)

- Cytokine Signaling in Immune system (Mus musculus)
  - Signaling by Interleukins (Mus musculus)
    - Interleukin-17 signaling (Mus musculus)
      - MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
- Innate Immune System (Mus musculus)
  - Fc epsilon receptor (FCERI) signaling (Mus musculus)
    - FCERI mediated MAPK activation (Mus musculus)
      - Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
  - Toll-like Receptor Cascades (Mus musculus)
    - Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
      - MyD88 cascade initiated on plasma membrane (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
    - Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
      - Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
      - Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
        
        MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
    - Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
      - MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
    - Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
      - MyD88-independent TLR4 cascade (Mus musculus)
        
        TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
      - MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
    - Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
      - MyD88 cascade initiated on plasma membrane (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
    - Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
      - MyD88 dependent cascade initiated on endosome (Mus musculus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)
    - Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
      - MyD88 dependent cascade initiated on endosome (Mus musculus)
        
        TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
        
        MAP kinase activation (Mus musculus)
        
        JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
        
        Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
        
        MAPK8,9,10 [cytosol] (Mus musculus)
        
        MAPK9 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9WTU6

Reference Genes

BioGPS Gene:26420

ENSEMBL:ENSMUSG00000020366

KEGG:mmu:26420

Monarch:26420

NCBI Gene:26420

UCSC:Q9WTU6

Reference Transcript

Other Identifiers

101362_at

10375634

108719_at

138075_at

1421876_at

1421877_at

1421878_at

17249057

26420

4421423

4454957

4465455

4478542

4525928

4547596

4600723

4615394

4651060

4672766

4693928

4707259

4734206

4861979

4935397

4955818

5003510

5113750

5145842

5189201

5215465

5252115

5267951

5316228

5360787

5462265

5476125

5534615

5578268

5581460

A_51_P190541

A_52_P27244

A_52_P311566

A_55_P1973289

GE37128

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0004705

GO:0004707

GO:0004712

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005739

GO:0005829

GO:0005886

GO:0006468

GO:0006954

GO:0007254

GO:0010628

GO:0010744

GO:0016301

GO:0016607

GO:0016740

GO:0031398

GO:0032436

GO:0034614

GO:0042752

GO:0043488

GO:0046686

GO:0048511

GO:0050804

GO:0061157

GO:0061833

GO:0071803

GO:0090594

GO:0097190

GO:0098685

GO:0106310

GO:0140096

GO:1900017

GO:2001235

ILMN_1218582

ILMN_2554666

ILMN_2591066

ILMN_2716527

Msa.13906.0_s_at

Msa.39525.0_s_at

Msa.39534.0_s_at

mMC007842

Participates

as a member of

MAPK8,9,10 [cytosol] (Mus musculus)

Other forms of this molecule

phospho-p-T183,Y185-MAPK9 [cytosol]

phospho-p-T183,Y185-MAPK9 [nucleoplasm]

Inferred From

MAPK9 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSMUSP00000042744, ENSMUSP00000104807, ENSMUST00000164643, ENSMUSP00000099839, ENSMUSG00000020366, ENSMUST00000102778, ENSMUSP00000136977, ENSMUST00000178543, ENSMUST00000043321, ENSMUST00000020634, ENSMUSP00000132864, ENSMUST00000109178, ENSMUST00000109179, ENSMUSP00000020634, ENSMUSP00000104808

ZINC - Substances

MK09_MOUSE

ZINC target

Q9WTU6

PRO

Q9WTU6

MGI

1346862

ZINC - Predictions - Purchasable

MK09_MOUSE

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