Reactome | Insl5 [extracellular region]

Insl5 [extracellular region]

Stable Identifier

R-MMU-444855

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

extracellular region

Synonyms

INSL5(23-48), Q9WUG6

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Relaxin receptors (Mus musculus)
        
        Relaxin 3 receptor 2 binds relaxin 3 and INSL5 (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)
        
        RXFP4:RXFP4 ligands [plasma membrane] (Mus musculus)
        
        RXFP4 ligands [extracellular region] (Mus musculus)
        
        Insulin-like peptide 5 [extracellular region] (Mus musculus)
        
        Insl5 [extracellular region] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9WUG6

Gene Names

Insl5

Reference Genes

BioGPS Gene:23919 Insl5

ENSEMBL:ENSMUSG00000066090

ENSEMBL:ENSMUSG00000066090.6 Insl5

KEGG Gene (Mus musculus):23919 Insl5

Monarch:23919 Insl5

NCBI Gene:23919 Insl5

UCSC:Q9WUG6 Insl5

Reference Transcript

Other Identifiers

10514708

114713_at

1449493_at

17427655

23919

4335391

4340322

4371373

4381717

4720836

4984569

5314082

5344972

5519739

5523842

A_51_P428305

A_55_P2255325

GE35612

GO:0001664

GO:0005179

GO:0005576

GO:0007165

GO:0023052

GO:0030312

GO:0031012

GO:0048018

GO:0062023

GO:0098772

GO:2000253

ILMN_2608858

mMC006669

Participates

as a component of

Insulin-like peptide 5 [extracellular region] (Mus musculus)

Other forms of this molecule

Insl5 [extracellular region]

Inferred From

INSL5(23-48) [extracellular region] (Homo sapiens)

Cross References

RefSeq

NP_001277577.1, NP_035961.1

Ensembl

ENSMUSP00000081416, ENSMUST00000084382, ENSMUSG00000066090

PRO

Q9WUG6

MGI

1346085

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