Reactome | phospho-p-S154,T436-PAK3 [plasma membrane]

phospho-p-S154,T436-PAK3 [plasma membrane]

Stable Identifier

R-MMU-3928479

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Q61036

Locations in the PathwayBrowser

Expand all

Developmental Biology (Mus musculus)

- Nervous system development (Mus musculus)
  - Axon guidance (Mus musculus)
    - EPH-Ephrin signaling (Mus musculus)
      - Ephrin signaling (Mus musculus)
        
        PAKs autophosphorylate (Mus musculus)
        
        EPHBs:p-3Y-EFNBs:SRC,FYN:GRB4:p-GIT1:ARHGEF7:RAC1:GTP:p-PAK1,3 [plasma membrane] (Mus musculus)
        
        p-PAK1/3, 2 [plasma membrane] (Mus musculus)
        
        phospho-p-S154,T436-PAK3 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q61036 Pak3

Gene Names

Pak3, Pak-3, Pakb, Stk4

Chain

chain:1-559

Reference Genes

BioGPS Gene:18481 Pak3

KEGG:mmu:18481 Pak3

Monarch:18481 Pak3

NCBI Gene:18481 Pak3

UCSC:Q61036 Pak3

Reference Transcript

Other Identifiers

10602198

116952_at

1417923_at

1417924_at

1435486_at

1437318_at

161021_at

17538320

18481

4356103

4445949

4487541

4557067

4557736

4600790

4601413

4610464

4639495

4682626

4688038

4697556

4745881

4751624

4856025

4858156

4996636

5097632

5108735

5141332

5172306

5188711

5199365

5256709

5342187

5374847

5405342

5409260

5427894

5491378

5611577

A_51_P218345

A_52_P629112

A_52_P84928

A_55_P2022569

A_66_P107062

GE1568671

GO:0000165

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0004708

GO:0005515

GO:0005524

GO:0005737

GO:0005829

GO:0006468

GO:0007409

GO:0009267

GO:0014069

GO:0016301

GO:0016358

GO:0016477

GO:0016740

GO:0017124

GO:0030833

GO:0031267

GO:0032956

GO:0035556

GO:0043226

GO:0043408

GO:0046872

GO:0048856

GO:0048870

GO:0050770

GO:0060996

GO:0060997

GO:0098978

GO:0099175

GO:0106310

GO:0140096

ILMN_1216639

U39738_s_at

mMC025801

Participates

as a member of

p-PAK1/3, 2 [plasma membrane] (Mus musculus)

Other forms of this molecule

phospho-p-S154,T436-PAK3 [cytosol]

Pak3 [cytosol]

Inferred From

p-S154,T436-PAK3 [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 154 (in Homo sapiens)

Coordinate

154

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-threonine at 436 (in Homo sapiens)

Coordinate

436

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_032804.2, XP_036017738.1, XP_036017737.1, NP_001181977.1, XP_036017739.1, XP_030107110.1, XP_036017740.1, NP_001181978.1, XP_030107109.1, XP_030107108.1, XP_030107111.1, XP_036017734.1, XP_006528816.1, XP_011246092.1, XP_006528817.1, XP_036017736.1, XP_036017735.1, XP_006528815.1

ENSEMBL

ENSMUST00000112868, ENSMUST00000112865, ENSMUSP00000108485, ENSMUSP00000108484, ENSMUSP00000108486, ENSMUST00000112863, ENSMUST00000112864, ENSMUST00000033640, ENSMUSG00000031284, ENSMUSP00000108489, ENSMUST00000172330, ENSMUSP00000033640, ENSMUSP00000126562

IntEnz

2.7.11.1

PRO

Q61036

MGI

1339656

PDB

1EES

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P60953 CDC42	4	CDC42 [plasma membrane] (R-HSA-449545) CDC42 [cytosol] (R-HSA-442630) Ub-CDC42 [plasma membrane] (R-HSA-9959463) CDC42 [endoplasmic reticulum membrane] (R-HSA-5672086)	0.656	3