Reactome | Glp1r [plasma membrane]

Glp1r [plasma membrane]

Stable Identifier

R-MMU-381684

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

GLP1R, O35659

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (s) signalling events (Mus musculus)
      - Liganded Gs-activating GPCR acts as a GEF for Gs (Mus musculus)
        
        GPCR:ligand complexes that act on Gs:Heterotrimeric G-protein Gs (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
        
        GLP-1:GLP-1R [plasma membrane] (Mus musculus)
        
        Glp1r [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs:Heterotrimeric G-protein Gs (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gs [plasma membrane] (Mus musculus)
        
        GLP-1:GLP-1R [plasma membrane] (Mus musculus)
        
        Glp1r [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class B/2 (Secretin family receptors) (Mus musculus)
      - Glucagon-type ligand receptors (Mus musculus)
        
        GLP1R binds GLP1 (Mus musculus)
        
        GLP1:GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Mus musculus)
        
        GLP-1:GLP-1R [plasma membrane] (Mus musculus)
        
        Glp1r [plasma membrane] (Mus musculus)
        
        GLP1R:Heterotrimeric G(s):GDP [plasma membrane] (Mus musculus)
        
        Glp1r [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:O35659

Gene Names

Glp1r

Reference Genes

BioGPS Gene:14652 Glp1r

ENSEMBL:ENSMUSG00000024027

KEGG:mmu:14652 Glp1r

Monarch:14652 Glp1r

NCBI Gene:14652 Glp1r

UCSC:O35659 Glp1r

Reference Transcript

RefSeq:NM_021332.2 Glp1r

Other Identifiers

10443690

1422330_at

1430642_at

14652

17335726

4309352

4325186

4373043

4547912

4647441

4677064

4824692

4901893

4941599

5002179

5027598

5124831

5213044

5445539

5477721

5565990

5590941

A_51_P275077

A_55_P2132089

A_55_P2209053

GE104542

GE120570

GO:0004888

GO:0004930

GO:0004967

GO:0005886

GO:0006886

GO:0007165

GO:0007166

GO:0007186

GO:0007189

GO:0007204

GO:0007218

GO:0007611

GO:0008016

GO:0008528

GO:0015031

GO:0016020

GO:0017046

GO:0031204

GO:0038023

GO:0044508

GO:0045776

GO:0045777

GO:0046879

GO:0050877

GO:0055085

GO:0071377

GO:1990911

ILMN_2479317

ILMN_2500908

ILMN_2608776

mMC002748

mMC008165

mMC012663

Participates

as a component of

Inferred From

GLP1R [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_067307.2

ENSEMBL

ENSMUSG00000024027, ENSMUST00000236038, ENSMUSP00000157572, ENSMUST00000114574, ENSMUSP00000110221

ZINC - Substances

GLP1R_MOUSE

ZINC target

O35659

PRO

O35659

GlyGen

O35659

MGI

99571

ZINC - Predictions - Purchasable

GLP1R_MOUSE