Reactome | Ccp110 [cytosol]

Ccp110 [cytosol]

Stable Identifier

R-MMU-380261

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

CCP110, Q7TSH4

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Deubiquitination (Mus musculus)
    - Ub-specific processing proteases (Mus musculus)
      - USP33 deubiquitinates CCP110,ARRB (Mus musculus)
        
        USP33:CCP110,ARRB1,ARRB2 [cytosol] (Mus musculus)
        
        CCP110,ARRB2,(ARRB1) [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)

Organelle biogenesis and maintenance (Mus musculus)

- Cilium Assembly (Mus musculus)
  - Anchoring of the basal body to the plasma membrane (Mus musculus)
    - C2CD3 and OFD1 recruit 5 distal appendage proteins to the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - C2CD3 binds the mother centriole (Mus musculus)
      - mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - CP110 and CEP97 dissociate from the centriole (Mus musculus)
      - Ccp110 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - MARK4 binds ODF2 in the centriole (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - centrosome:C2CD2:distal appendage proteins:TTBK2:MARK4 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
    - The distal appendage proteins recruit TTBK2 (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)
      - Centrosome:C2CD3:distal appendage proteins:TTBK2 [cytosol] (Mus musculus)
        
        Centrosome:C2CD3:distal appendage proteins [cytosol] (Mus musculus)
        
        mother centriole:C2CD3 [cytosol] (Mus musculus)
        
        mother centriole [cytosol] (Mus musculus)
        
        Ccp110 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q7TSH4

Gene Names

Ccp110

Reference Genes

BioGPS Gene:101565 Ccp110

ENSEMBL:ENSMUSG00000033904

KEGG:mmu:101565 Ccp110

Monarch:101565 Ccp110

NCBI Gene:101565 Ccp110

UCSC:Q7TSH4 Ccp110

Reference Transcript

RefSeq:NM_182995.1 Ccp110

Other Identifiers

101565

10556640

114168_at

138208_at

1455218_at

17482160

4369630

4423873

4424873

4438813

4464355

4558584

4651346

4709645

4817240

4869337

4877114

4890807

4923952

4932126

4969579

5009169

5020373

5075200

5096874

5122008

5139466

5173333

5194781

5219921

5242649

5256331

5309295

5346394

5381683

5386335

5401970

5417331

5464587

5476574

5498562

5597218

5606893

A_52_P344160

A_52_P479038

A_55_P2047559

GE1530738

GO:0005515

GO:0005737

GO:0005813

GO:0005814

GO:0005815

GO:0005856

GO:0005929

GO:0007099

GO:0030030

GO:0032053

GO:0032465

GO:0032991

GO:0043226

GO:0044782

GO:0045724

GO:0051298

GO:1902018

GO:1903723

ILMN_1224182

ILMN_1228426

ILMN_3006575

mMC021711

Participates

as a candidate of

RHOV effectors [cytosol] (Mus musculus)

as an output of

CP110 and CEP97 dissociate from the centriole (Mus musculus)

as a component of

as a member of

CCP110,ARRB2,(ARRB1) [cytosol] (Mus musculus)

Other forms of this molecule

Ccp110 [cytosol]

Inferred From

CCP110 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_892040.1

ENSEMBL

ENSMUST00000038650, ENSMUSP00000038881, ENSMUSP00000102167, ENSMUSG00000033904, ENSMUST00000106557

PRO

Q7TSH4

MGI

2141942

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q6A078	3	Cep290 [extracellular region] (R-MMU-6806291) Cep290 [specific granule lumen] (R-MMU-6799524) Cep290 [cytosol] (R-MMU-380275)	0.623	3

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