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Spc24 [cytosol]
Stable Identifier
R-MMU-375297
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
SPC24, Q9D083
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Amplification of signal from the kinetochores (Mus musculus)
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Mus musculus)
MAD2 associates with the Mad1 kinetochore complex (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
MAD2 converted to an inhibitory state via interaction with Mad1 (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Mad1 binds kinetochore (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Release of activated MAD2 from kinetochores (Mus musculus)
Kinetochore:Mad1:MAD2 Complex [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Mad1:kinetochore complex [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
ESPL1 (Separase) cleaves centromeric cohesin (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Separation of sister chromatids (Mus musculus)
Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore:Microtubules [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Mitotic Prometaphase (Mus musculus)
EML4 and NUDC in mitotic spindle formation (Mus musculus)
EML4 recruits NUDC to mitotic spindle (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Resolution of Sister Chromatid Cohesion (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Kinetochore assembly (Mus musculus)
Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Sister Centromere:Kinetochore [chromosome, centromeric region] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
PP2A-B56 dephosphorylates centromeric cohesin (Mus musculus)
p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Phosphorylation of cohesin by PLK1 at centromeres (Mus musculus)
Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Mus musculus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
CDC42:GTP recruits DIAPH2-2 to kinetochores (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Kinetochore capture of astral microtubules is positively regulated by CDC42:GTP:p-S196-DIAPH2-2 (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Kinetochore:CDC42:GTP:p-S196-DIAPH2-2 [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
Microtubule-bound kinetochore [cytosol] (Mus musculus)
Kinetochore [cytosol] (Mus musculus)
KMN network [cytosol] (Mus musculus)
NDC80 complex [cytosol] (Mus musculus)
Spc24 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q9D083
Gene Names
Spc24
Reference Genes
BioGPS Gene:67629 Spc24
ENSEMBL:ENSMUSG00000074476
ENSEMBL:ENSMUSG00000074476.7 Spc24
KEGG Gene (Mus musculus):67629 Spc24
Monarch:67629 Spc24
NCBI Gene:67629 Spc24
UCSC:Q9D083 Spc24
Reference Transcript
RefSeq:NM_026282.5 Spc24
Other Identifiers
10591556
110297_at
1431087_at
17524752
4484315
4623384
4690977
4716043
4766375
4859490
4932071
5030516
5063572
5300335
5345579
67629
A_51_P214209
A_55_P2056473
A_55_P2738634
GO:0000278
GO:0000775
GO:0000776
GO:0005634
GO:0005654
GO:0005694
GO:0005730
GO:0007049
GO:0007059
GO:0007094
GO:0008017
GO:0008092
GO:0008608
GO:0023052
GO:0031262
GO:0043226
GO:0051301
GO:0140014
ILMN_2615709
ILMN_2750890
ILMN_2948272
mMC004121
mMC024626
Participates
as a component of
NDC80 complex [cytosol] (Mus musculus)
Inferred From
SPC24 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_080558.1
Ensembl
ENSMUSP00000096541
,
ENSMUST00000217382
,
ENSMUSP00000150475
,
ENSMUST00000098942
,
ENSMUSG00000074476
PRO
Q9D083
MGI
1914879
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