Reactome | Lmna [nuclear envelope]

Lmna [nuclear envelope]

Stable Identifier

R-MMU-352249

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nuclear envelope

Synonyms

LMNA(231-664), P48678

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P48678 Lmna

Gene Names

Lmna, Lmn1

Chain

chain:1-662, chain:1-647, propeptide:648-662, propeptide:663-665

Reference Genes

BioGPS Gene:16905 Lmna

KEGG:mmu:16905 Lmna

Monarch:16905 Lmna

NCBI Gene:16905 Lmna

UCSC:P48678 Lmna

Reference Transcript

Participates

as an output of

Caspase-mediated cleavage of Lamin A (Mus musculus)

Other forms of this molecule

phospho-Lmna [nucleoplasm]

Lmna [nucleoplasm]

Lmna [cytosol]

Lmna [nuclear envelope]

Lmna [nucleoplasm]

Inferred From

LMNA(231-664) [nuclear envelope] (Homo sapiens)

Cross References

RefSeq

NP_001104572.1, XP_006501136.1, NP_062263.1, NP_001002011.2

ENSEMBL

ENSMUSP00000029699, ENSMUST00000120377, ENSMUST00000036252, ENSMUSP00000113093, ENSMUSP00000040265, ENSMUST00000029699, ENSMUSG00000028063

PRO

P48678

GlyGen

P48678

MGI

96794

PDB

1UFG

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31750 Akt1	12	phospho-p-T308,S473-AKT1 [nucleoplasm] (R-MMU-198357) phospho-p-T308,S473-AKT1 [cytosol] (R-MMU-198356) phospho-p-S473-AKT1 [plasma membrane] (R-MMU-377265) AKT1 [plasma membrane] (R-MMU-199416) AKT1 [cytosol] (R-MMU-58252) phospho-p-T308-AKT1 [cytosol] (R-MMU-198634) phospho-p-Y315,Y326-AKT1 [cytosol] (R-MMU-8848757) p-T308,S473-Akt1 [cytosol] (R-MMU-162346) phospho-p-T308,S473-AKT1 [plasma membrane] (R-MMU-199430) Akt1 [cytosol] (R-MMU-189709) phospho-p-S473-AKT1 [cytosol] (R-MMU-9841264) p-T308,S473-Akt1 [plasma membrane] (R-MMU-1445123)	0.564	2
UniProt:Q5FW52 MLIP			0.488	2

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