Reactome | RAPGEF4 [plasma membrane]

RAPGEF4 [plasma membrane]

Stable Identifier

R-MMU-3008666

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

Q9EQZ6

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9EQZ6

Reference Genes

BioGPS Gene:56508 RAPGEF4

ENSEMBL:ENSMUSG00000049044

KEGG:mmu:56508 RAPGEF4

Monarch:56508 RAPGEF4

NCBI Gene:56508 RAPGEF4

UCSC:Q9EQZ6 RAPGEF4

Reference Transcript

Participates

as an input of

cAMP activates EPAC2 (Mus musculus)

as a component of

RAPGEF4:cAMP Complex [plasma membrane] (Mus musculus)

as a member of

Rap1 cAMP-GEFs [plasma membrane] (Mus musculus)

Inferred From

RAPGEF4 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_062662.1, NP_001191094.1, NP_001191095.1

ENSEMBL

ENSMUSP00000088336, ENSMUST00000090826, ENSMUSG00000049044, ENSMUSP00000099759, ENSMUST00000102698

PRO

Q9EQZ6

GlyGen

Q9EQZ6

MGI

1917723

PDB

4MH0, 4F7Z, 4MGK, 3CF6, 4MGI, 1O7F, 2BYV, 4MGZ, 4MGY

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01112 HRAS	20	S-Farn-Me-2xPalmS HRAS [plasma membrane] (R-HSA-9647912) HRAS [plasma membrane] (R-HSA-62717) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-proHRAS [endoplasmic reticulum membrane] (R-HSA-9647918) proHRAS [cytosol] (R-HSA-9647765) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS G12C [plasma membrane] (R-HSA-9656561) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G13R [plasma membrane] (R-HSA-6802368)	0.556	3

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