Activin AB/B binds Activin Receptor Acvr2a:Acvr1c

Stable Identifier
R-MMU-2470495
Type
Reaction
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Activin AB/B binds Activin Receptor Acvr2a:Acvr1c

Activin B or Activin AB, but not Activin A binds Activin receptors containing the type I receptor Acvr1c (Alk7) with the type II receptor Acvr2a (Tsuchida et al. 2004, Bernard et al. 2006). Binding to receptors containing Acvr2b is inferred.

Literature References
PubMed ID Title Journal Year
17040568 Activin B can signal through both ALK4 and ALK7 in gonadotrope cells

Bernard, DJ, Lee, KB, Santos, MM

Reprod. Biol. Endocrinol. 2006
15196700 Activin isoforms signal through type I receptor serine/threonine kinase ALK7

Tsuchida, K, Nakatani, M, Yamakawa, N, Hashimoto, O, Hasegawa, Y, Sugino, H

Mol. Cell. Endocrinol. 2004
Participants
Orthologous Events
Authored
Reviewed
Created