Reactome | Pcsk1 [secretory granule lumen]

Pcsk1 [secretory granule lumen]

Stable Identifier

R-MMU-216794

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

secretory granule lumen

Synonyms

Convertase PC1/3 (in immature granule)

Literature References

PubMed ID	Title	Journal	Year
8397508	Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2 Benjannet, S, Rondeau, N, Paquet, L, Boudreault, A, Lazure, C, Chrétien, M, Seidah, NG	Biochem. J.	1993
8449925	Purification and characterization of the prohormone convertase PC1(PC3) Zhou, Y, Lindberg, I	J. Biol. Chem.	1993

External Reference Information

External Reference

UniProt:P63239 Pcsk1

Gene Names

Pcsk1, Att-1, Nec-1, Nec1

Chain

signal peptide:1-27, propeptide:28-110, chain:111-753

Reference Genes

BioGPS Gene:18548 Pcsk1

KEGG:mmu:18548 Pcsk1

Monarch:18548 Pcsk1

NCBI Gene:18548 Pcsk1

UCSC:P63239 Pcsk1

Reference Transcript

Other Identifiers

10406229

1421396_at

170227_at

17288677

18548

4313160

4556107

4569370

4619798

4650069

4687841

4793424

4849520

4867854

4879131

4915008

5159577

5235000

5255043

5272036

5288024

5453722

5468206

5615560

94694_at

A_52_P164524

A_52_P500979

GE104868

GE36725

GO:0004175

GO:0004252

GO:0005615

GO:0005788

GO:0006508

GO:0008233

GO:0008236

GO:0016020

GO:0016485

GO:0016486

GO:0016787

GO:0030070

GO:0030133

GO:0030141

GO:0031410

GO:0034774

GO:0042802

GO:0043005

GO:0043043

ILMN_1251728

ILMN_2576158

ILMN_2680894

m58589_s_at

mMC018120

Other forms of this molecule

Pcsk1 [secretory granule lumen]

Proprotein convertase 1 [endoplasmic reticulum lumen]

Cross References

RefSeq

XP_006517217.1, NP_038656.1, NP_001413214.1, NP_001413216.1

ENSEMBL

ENSMUSG00000021587, ENSMUST00000022075, ENSMUSP00000022075

PRO

P63239

GlyGen

P63239

MGI

97511

PDB

1KN6, 2KE3, 2KDT

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63239 Pcsk1	3	Pcsk1 [secretory granule lumen] (R-MMU-216794) Pcsk1 [secretory granule lumen] (R-MMU-378951) Proprotein convertase 1 [endoplasmic reticulum lumen] (R-MMU-181794)	0.558	2

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