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Grb7 [cytosol]
Stable Identifier
R-MMU-204819
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
GRB7, Q03160
Locations in the PathwayBrowser
Expand all
Developmental Biology (Mus musculus)
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
RET signaling (Mus musculus)
2x p-5Y-RET:GDNF:GFRA complexes bind GRB7,10 (Mus musculus)
2x p-5Y-RET:GDNF:GFRA complexes:GRB7,GRB10 [plasma membrane] (Mus musculus)
GRB7,GRB10 [cytosol] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
GRB7,GRB10 [cytosol] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Hemostasis (Mus musculus)
Cell surface interactions at the vascular wall (Mus musculus)
Tie2 Signaling (Mus musculus)
Interaction of Tie2 and Grb7 (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Tie2:Grb7 complex [plasma membrane] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ERBB2 (Mus musculus)
GRB7 events in ERBB2 signaling (Mus musculus)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Mus musculus)
Grb7 [cytosol] (Mus musculus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Signaling by PDGF (Mus musculus)
Downstream signal transduction (Mus musculus)
Grb7 binds to the active PDGF receptor (Mus musculus)
Grb7 [cytosol] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Signaling by SCF-KIT (Mus musculus)
Interaction of other adapter proteins with p-KIT (Mus musculus)
Adapter proteins [cytosol] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Adapter proteins:p-KIT complex [plasma membrane] (Mus musculus)
Adapter proteins [cytosol] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase cycle (Mus musculus)
RND1 GTPase cycle (Mus musculus)
RND1 binds effectors (Mus musculus)
RND1 effectors [cytosol] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
RND1:GTP:RND1 effectors [plasma membrane] (Mus musculus)
RND1 effectors [cytosol] (Mus musculus)
Grb7 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q03160
Gene Names
Grb7
Reference Genes
BioGPS Gene:14786 Grb7
ENSEMBL:ENSMUSG00000019312
KEGG:mmu:14786 Grb7
Monarch:14786 Grb7
NCBI Gene:14786 Grb7
UCSC:Q03160 Grb7
Reference Transcript
RefSeq:NM_010346.2 Grb7
RefSeq:XM_006532233.1 Grb7
Other Identifiers
103095_at
10380927
1448227_at
14786
17256033
4339392
4485834
4530595
4542789
4562025
4568270
4573920
4621228
4626055
4728672
4883910
4895438
4924880
4969256
5062844
5156846
5182095
5236534
5359247
5474908
5515930
GO:0003723
GO:0005515
GO:0005737
GO:0005829
GO:0005886
GO:0005925
GO:0007165
GO:0008289
GO:0010494
GO:0017148
GO:0019901
GO:0030335
GO:0034063
GO:0035091
GO:0042802
GO:0042995
GO:0043226
GO:0070161
ILMN_2773169
Msa.721.0_at
aa216863_s_at
mMC005192
Participates
as a member of
RND1 effectors [cytosol] (Mus musculus)
GRB7,GRB10 [cytosol] (Mus musculus)
Adapter proteins [cytosol] (Mus musculus)
as an input of
Interaction of Tie2 and Grb7 (Mus musculus)
Grb7 binds to the active PDGF receptor (Mus musculus)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Mus musculus)
as a component of
Tie2:Grb7 complex [plasma membrane] (Mus musculus)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Mus musculus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Mus musculus)
Inferred From
GRB7 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_006532296.1
,
NP_034476.1
ENSEMBL
ENSMUST00000019456
,
ENSMUSP00000019456
PRO
Q03160
MGI
102683
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P70372
6
phospho-Elavl1 [cytosol]
(R-MMU-450376)
phospho-Elavl1 [cytosol]
(R-MMU-450448)
Elavl1 [cytosol]
(R-MMU-450582)
phospho-Elavl1 [nucleoplasm]
(R-MMU-450532)
phospho-Elavl1 [nucleoplasm]
(R-MMU-450576)
Elavl1 [nucleoplasm]
(R-MMU-450601)
0.65
7
UniProt:Q80ZW7 Q80ZW7
0.556
4
UniProt:Q02858 Tek
4
Phosphorylated_Tie2 [plasma membrane]
(R-MMU-211116)
Tie2 [plasma membrane]
(R-MMU-211118)
TEK [plasma membrane]
(R-MMU-197755)
phospho-p-5Y,S1119-TEK [plasma membrane]
(R-MMU-204772)
0.548
3
UniProt:Q03135 CAV1
5
CAV1 [Golgi membrane]
(R-HSA-204504)
CAV1 [plasma membrane]
(R-HSA-534994)
CAV1 [lipid droplet]
(R-HSA-163510)
CAV1 [endocytic vesicle membrane]
(R-HSA-535009)
CAV1 [early endosome membrane]
(R-HSA-5368451)
0.532
3
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