Reactome | CSNK2A2 [cytosol]

CSNK2A2 [cytosol]

Stable Identifier

R-MMU-201721

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

O54833

Locations in the PathwayBrowser

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Autophagy (Mus musculus)

- Macroautophagy (Mus musculus)
  - Selective autophagy (Mus musculus)
    - Mitophagy (Mus musculus)
      - Receptor Mediated Mitophagy (Mus musculus)
        
        FUNDC1 is phosphorylated by CK2 (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Cell Cycle (Mus musculus)

- Cell Cycle, Mitotic (Mus musculus)
  - M Phase (Mus musculus)
    - Mitotic Prometaphase (Mus musculus)
      - Condensation of Prometaphase Chromosomes (Mus musculus)
        
        CK2 phosphorylates condensin I subunits (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Cell-Cell communication (Mus musculus)

- Cell junction organization (Mus musculus)
  - Cell-cell junction organization (Mus musculus)
    - Adherens junctions interactions (Mus musculus)
      - Regulation of Homotypic Cell-Cell Adhesion (Mus musculus)
        
        Regulation of Expression and Function of Type I Classical Cadherins (Mus musculus)
        
        Regulation of CDH1 Expression and Function (Mus musculus)
        
        Regulation of CDH1 posttranslational processing and trafficking to plasma membrane (Mus musculus)
        
        Cytosolic tail of CDH1 is phosphorylated (Mus musculus)
        
        (CK2) [cytosol] (Mus musculus)
        
        CK2 (A1:A2:B) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CK2 (A2:B) [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Developmental Biology (Mus musculus)

- Nervous system development (Mus musculus)
  - Axon guidance (Mus musculus)
    - L1CAM interactions (Mus musculus)
      - Signal transduction by L1 (Mus musculus)
        
        Phosphorylation of L1 by CK-II (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        pL1:CK-II [plasma membrane] (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Immune System (Mus musculus)

- Adaptive Immune System (Mus musculus)
  - Regulation of T cell activation by CD28 family (Mus musculus)
    - Co-inhibition by PD-1 (Mus musculus)
      - Regulation of PD-L1(CD274) expression (Mus musculus)
        
        Regulation of PD-L1(CD274) Post-translational modification (Mus musculus)
        
        SPOP-mediated proteasomal degradation of PD-L1(CD274) (Mus musculus)
        
        CK2 phosphorylates CD274 (Mus musculus)
        
        CK2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Metabolism (Mus musculus)

- Metabolism of lipids (Mus musculus)
  - Phospholipid metabolism (Mus musculus)
    - Glycerophospholipid biosynthesis (Mus musculus)
      - Synthesis of PC (Mus musculus)
        
        Casein kinase II phosphorylates STARD10 (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Metabolism of proteins (Mus musculus)

- Protein folding (Mus musculus)
  - Chaperonin-mediated protein folding (Mus musculus)
    - Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Mus musculus)
      - CK2 phosphorylates PDCL (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - PTEN Regulation (Mus musculus)
      - Regulation of PTEN stability and activity (Mus musculus)
        
        Casein kinase II phosphorylates PTEN (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
- Signaling by WNT (Mus musculus)
  - TCF dependent signaling in response to WNT (Mus musculus)
    - WNT mediated activation of DVL (Mus musculus)
      - CSNK2-mediated phosphorylation of DVL (Mus musculus)
        
        Casein kinase II [cytosol] (Mus musculus)
        
        CSNK2(A1:A1/A1:A2/A2:A2) [cytosol] (Mus musculus)
        
        CSNK2A1:CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)
        
        CSNK2A2 dimer [cytosol] (Mus musculus)
        
        CSNK2A2 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:O54833 Csnk2a2

Gene Names

Csnk2a2

Chain

chain:1-350

Reference Genes

BioGPS Gene:13000 Csnk2a2

KEGG:mmu:13000 Csnk2a2

Monarch:13000 Csnk2a2

NCBI Gene:13000 Csnk2a2

UCSC:O54833 Csnk2a2

Reference Transcript

RefSeq:NM_009974.3 Csnk2a2

Other Identifiers

10580885

115363_at

115781_at

13000

1419935_s_at

1429301_at

1429302_at

1453099_at

1453100_at

1460646_at

163820_at

17512009

4356169

4563183

4584809

4647271

4706922

4786109

4827792

4961913

5196559

5220670

5224462

5318452

5363160

5379337

5400734

5485429

5496630

5515246

5537204

5582356

5611532

94482_at

94483_at

98245_at

A_51_P202964

A_52_P207614

A_52_P405362

A_55_P2742555

A_66_P117655

C77789_rc_at

C77789_rc_g_at

GE35263

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005634

GO:0005737

GO:0005829

GO:0005956

GO:0006281

GO:0006302

GO:0006468

GO:0006915

GO:0006974

GO:0007283

GO:0016055

GO:0016301

GO:0016740

GO:0022414

GO:0031519

GO:0032435

GO:0051726

GO:0106310

GO:0140096

GO:1905818

ILMN_1227008

ILMN_1228485

ILMN_1240588

ILMN_2632447

ILMN_2739039

Msa.23113.0_s_at

Msa.24665.0_s_at

mMC021431

mMR001360

Participates

as a component of

Other forms of this molecule

CK2alpha' [cytosol]

CSNK2A2 [nucleoplasm]

Inferred From

CSNK2A2 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_034104.1

ENSEMBL

ENSMUSP00000055919, ENSMUSG00000046707, ENSMUST00000212214, ENSMUSP00000148404, ENSMUST00000056919

ZINC - Substances

CSK22_MOUSE

ZINC target

O54833

PRO

O54833

GlyGen

O54833

MGI

88547

ZINC - Predictions - Purchasable

CSK22_MOUSE

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