Reactome | Il1rl1 [plasma membrane]

Il1rl1 [plasma membrane]

Stable Identifier

R-MMU-197594

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

IL1RL1, P14719

Locations in the PathwayBrowser

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Signal Transduction (Mus musculus)

- Intracellular signaling by second messengers (Mus musculus)
  - PIP3 activates AKT signaling (Mus musculus)
    - Negative regulation of the PI3K/AKT network (Mus musculus)
      - PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
        
        PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1 [plasma membrane] (Mus musculus)
        
        IL1RL1:IL33 [plasma membrane] (Mus musculus)
        
        Il1rl1 [plasma membrane] (Mus musculus)
    - PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
      - IL33:IL1RL1:IL1RAP-1:MYD88 dimer:IRAK1,IRAK4,TRAF6 [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1:MYD88 dimer [plasma membrane] (Mus musculus)
        
        IL33:IL1RL1:IL1RAP-1 [plasma membrane] (Mus musculus)
        
        IL1RL1:IL33 [plasma membrane] (Mus musculus)
        
        Il1rl1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P14719

Gene Names

Il1rl1

Reference Genes

BioGPS Gene:17082 Il1rl1

ENSEMBL:ENSMUSG00000026069

KEGG:mmu:17082 Il1rl1

Monarch:17082 Il1rl1

NCBI Gene:17082 Il1rl1

UCSC:P14719 Il1rl1

Reference Transcript

Other Identifiers

10345791

1422317_a_at

1425145_at

17082

17212211

4324712

4382803

4446539

4600672

4652372

4734179

4756335

4764010

4882581

4892072

4900950

4917429

4937878

4938662

4938825

4955148

5022326

5067631

5115925

5118123

5164939

5169704

5203015

5287722

5347941

5362224

5379246

5430455

5433823

5433845

98500_at

98501_at

A_51_P339793

A_52_P19955

A_52_P484194

A_55_P2027731

A_55_P2027737

GE36417

GO:0002113

GO:0002114

GO:0002826

GO:0004908

GO:0005515

GO:0005576

GO:0005829

GO:0005886

GO:0005925

GO:0006954

GO:0007165

GO:0009611

GO:0009897

GO:0009986

GO:0016020

GO:0016787

GO:0019221

GO:0030154

GO:0030225

GO:0032689

GO:0032722

GO:0032754

GO:0038172

GO:0043032

GO:0050727

GO:0050729

GO:0061809

GO:1901652

ILMN_1243504

ILMN_1244895

ILMN_2461338

ILMN_2461340

ILMN_2757615

ILMN_2757617

Msa.87.0_s_at

m24843_at

mMC023578

mMR001458

Participates

as an input of

IL33 binds IL1RL1 (Mus musculus)

as a component of

IL1RL1:IL33 [plasma membrane] (Mus musculus)

Other forms of this molecule

Il1rl1 [extracellular region]

Inferred From

IL1RL1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001407277.1, NP_001281100.1, NP_001407278.1, NP_034873.2, NP_001020773.1, NP_001407279.1

ENSEMBL

ENSMUSP00000133784, ENSMUSP00000134351, ENSMUST00000053043, ENSMUSG00000026069, ENSMUST00000097772, ENSMUSP00000095379, ENSMUST00000174335, ENSMUST00000173514, ENSMUSP00000054914

PRO

P14719

GlyGen

P14719

MGI

98427

PDB

5VI4

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q61730	1	Il1rap [plasma membrane] (R-MMU-445745)	0.564	3
UniProt:Q6PCT2 FBXL19	1	FBXL19 [cytosol] (R-HSA-8862607)	0.524	3