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EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane]
Stable Identifier
R-MMU-182928
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by EGFR (Mus musculus)
EGFR downregulation (Mus musculus)
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Mus musculus)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Mus musculus)
Localization of CBL:GRB2 to the membrane (Mus musculus)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Mus musculus)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Mus musculus)
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
CBL:GRB2 [cytosol]
(Mus musculus)
EGF-like ligands:p-6Y EGFR dimer [plasma membrane]
(Mus musculus)
Participates
as an output of
CBL escapes CDC42-mediated inhibition by down-regulating the adaptor molecule Beta-Pix (Mus musculus)
Localization of CBL:GRB2 to the membrane (Mus musculus)
as an input of
Phosphorylation of CBL (EGFR:GRB2:CBL) (Mus musculus)
Inferred From
EGF-like ligands:p-6Y-EGFR:CBL:GRB2 [plasma membrane]
(Homo sapiens)
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