Reactome | Anapc7 [nucleoplasm]

Anapc7 [nucleoplasm]

Stable Identifier

R-MMU-174204

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

ANAPC7, Q9WVM3

Locations in the PathwayBrowser

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Cell Cycle (Mus musculus)

- Cell Cycle, Mitotic (Mus musculus)
  - Regulation of mitotic cell cycle (Mus musculus)
    - APC/C-mediated degradation of cell cycle proteins (Mus musculus)
      - APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
        
        APC/C:Cdh1 polyubiquitinates SKP2 (Mus musculus)
        
        PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        APC/C:Cdh1-mediated degradation of Skp2 (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        PolyUb-SKP2:RB1:phospho-APC/C:Cdh1 complex [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        RB1 recruits APC/C:Cdh1 complex to SKP2 (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        RB1:SKP2:APC/C:Cdh1 [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
      - Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
        
        Phosphorylation of the APC/C (Mus musculus)
        
        Free APC/C phosphorylated by Cyclin B:Cdc2 (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Free APC/C phosphorylated by Plk1 (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
      - Autodegradation of Cdh1 by Cdh1:APC/C (Mus musculus)
        
        Degradation of multiubiquitinated Cdh1 (Mus musculus)
        
        multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Mus musculus)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Multiubiquitination of APC/C-associated Cdh1 (Mus musculus)
        
        multiubiquitinated Cdh1 associated with APC/C [nucleoplasm] (Mus musculus)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
      - Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
        
        Association of Cyclin A:Cdk2 with Cdh1 (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Dissociation of phospho-Cdh1 from the APC/C complex (Mus musculus)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Mus musculus)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)

Cellular responses to stimuli (Mus musculus)

- Cellular responses to stress (Mus musculus)
  - Cellular Senescence (Mus musculus)
    - Senescence-Associated Secretory Phenotype (SASP) (Mus musculus)
      - CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
      - CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Mus musculus)
        
        Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
      - Cdh1:APC/C complex binds EHMT1:EHMT2 (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
      - Cdh1:APC/C ubiquitinates EHMT1 and EHMT2 (Mus musculus)
        
        EHMT1:EHMT2:Cdh1:p-APC/C [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)
        
        Ub-EHMT1:Ub-EHMT2:Cdh1:p-APC/C [nucleoplasm] (Mus musculus)
        
        Cdh1:phospho-APC/C complex [nucleoplasm] (Mus musculus)
        
        phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)
        
        Anapc7 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9WVM3

Gene Names

Anapc7

Reference Genes

BioGPS Gene:56317 Anapc7

ENSEMBL:ENSMUSG00000029466

KEGG:mmu:56317 Anapc7

Monarch:56317 Anapc7

NCBI Gene:56317 Anapc7

UCSC:Q9WVM3 Anapc7

Reference Transcript

Other Identifiers

10525406

115414_at

116198_at

1418458_at

1441713_at

17442107

4322834

4341431

4352982

4396299

4442664

4471621

4481184

4538221

4616828

4653012

4781135

4911384

4972668

5113684

5113751

5231163

5257505

5259749

5281842

5296101

5368523

5460893

56317

A_51_P442481

A_52_P384134

A_55_P2075523

A_55_P2112330

A_55_P2731736

GE130232

GE37518

GO:0000792

GO:0005515

GO:0005634

GO:0005654

GO:0005680

GO:0005737

GO:0005819

GO:0005856

GO:0007420

GO:0015630

GO:0016567

GO:0019903

GO:0030163

GO:0031145

GO:0043226

GO:0045171

GO:0045842

GO:0048856

GO:0051301

GO:0060090

GO:0070936

GO:0070979

GO:0072686

GO:0140767

GO:0141198

ILMN_1220635

ILMN_2870688

ILMN_3161470

mMC000951

Participates

as a component of

phosphorylated anaphase promoting complex (APC/C) [nucleoplasm] (Mus musculus)

Other forms of this molecule

Anapc7 [cytosol]

Inferred From

ANAPC7 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_036021221.1, NP_062779.3

ENSEMBL

ENSMUSG00000029466, ENSMUST00000031422, ENSMUST00000122010, ENSMUSP00000031422, ENSMUSP00000113928

PRO

Q9WVM3

GlyGen

Q9WVM3

MGI

1929711

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