Reactome | Ndufa10 [mitochondrial inner membrane]

Ndufa10 [mitochondrial inner membrane]

Stable Identifier

R-MMU-163937

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

mitochondrial inner membrane

Synonyms

NDUFA10, Q99LC3

Locations in the PathwayBrowser

Expand all

Metabolism (Mus musculus)

- Aerobic respiration and respiratory electron transport (Mus musculus)
  - Respiratory electron transport (Mus musculus)
    - Complex I biogenesis (Mus musculus)
      - Intermediate 1 binds HP subcomplex to form Intermediate 2 (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
      - Intermediate 2 binds MT-ND1:NDUFAF5:NDUFAF6 to form a 315kDa subcomplex (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
      - ND4, ND5 bind the 550kDa complex to form the 815kDa complex (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
      - Peripheral arm subunits bind the 815kDa complex to form a 980kDa complex (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        980kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
      - The 315kDa subcomplex binds the 370kDa subcomplex to form the 550kDa complex (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
      - The MCIA complex, NDUFAF2-7 all dissociate from the 980kDa complex, resulting in Complex I (Mus musculus)
        
        980kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
        
        Complex I [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)
    - Complex I oxidises NADH to NAD+, reduces CoQ to CoQH2 (Mus musculus)
      - Complex I [mitochondrial inner membrane] (Mus musculus)
        
        815kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        550kDa complex (-MCIA, NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        315kDa subcomplex (-NDUFAF3,4,5,6,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        Intermediate 2 (-NDUFAF3,4,7,TIMMDC1) [mitochondrial inner membrane] (Mus musculus)
        
        HP subcomplex [mitochondrial inner membrane] (Mus musculus)
        
        NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)
        
        Ndufa10 [mitochondrial inner membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:Q99LC3

Gene Names

Ndufa10

Reference Genes

BioGPS Gene:67273 Ndufa10

ENSEMBL:ENSMUSG00000026260

KEGG:mmu:67273 Ndufa10

Monarch:67273 Ndufa10

NCBI Gene:67273 Ndufa10

UCSC:Q99LC3 Ndufa10

Reference Transcript

RefSeq:NM_024197.1 Ndufa10

Other Identifiers

10356657

134332_at

1418068_at

1448934_at

160284_at

17225564

4314840

4333761

4390717

4436837

4454238

4454450

4462256

4620909

4736388

4818187

4913266

4979228

5051294

5105517

5125330

5150169

5227834

5285445

5392163

5394355

5407322

5413261

5555091

5567721

67273

A_51_P272123

A_55_P2717274

A_66_P133882

GE40562

GO:0005737

GO:0005739

GO:0005743

GO:0005759

GO:0006091

GO:0006120

GO:0008137

GO:0009060

GO:0016491

GO:0042776

GO:0043209

GO:0045271

GO:0055085

GO:0055086

GO:1901135

GO:1902600

ILMN_2477629

ILMN_2657946

aa512555_at

aa512555_g_at

mMC008591

mMR028106

Participates

as a component of

NDUFA10:FAD [mitochondrial inner membrane] (Mus musculus)

Inferred From

NDUFA10 [mitochondrial inner membrane] (Homo sapiens)

Cross References

RefSeq

NP_077159.1

ENSEMBL

ENSMUSP00000027478, ENSMUSG00000026260, ENSMUST00000027478

PRO

Q99LC3

GlyGen

Q99LC3

MGI

1914523

PDB

6ZTQ, 6G2J, 8IBB, 8IBF, 8RGP, 8UCA, 8IB9, 8C2S, 7AK5, 7AK6, 8IB4, 8IAQ, 6G72, 8IC2, 8IB6, 8PW6, 8CA5, 8CA3, 8OLT, 8PW5, 7PSA, 8PW7, 8RGQ, 8IBD, 8RGT, 8OM1, 8RGR, 6ZR2, 7B93, 8IAO, 8IC4

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