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activated thrombin (factor IIa) [plasma membrane]
Stable Identifier
R-MMU-140811
Type
Complex
Species
Mus musculus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Hemostasis (Mus musculus)
Cell surface interactions at the vascular wall (Mus musculus)
Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin:thrombomodulin [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
Formation of Fibrin Clot (Clotting Cascade) (Mus musculus)
Common Pathway of Fibrin Clot Formation (Mus musculus)
Activated thrombin:thrombomodulin cleaves PROCR:Protein C to PROCR:Activated protein C (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin:thrombomodulin [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) + antithrombin III:heparin -> thrombin:antithrombin III:heparin (Mus musculus)
thrombin:SERPINC1:SERPINC1 activators [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) + thrombomodulin -> activated thrombin:thrombomodulin (Mus musculus)
activated thrombin:thrombomodulin [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
factor V -> factor Va + factor V activation peptide (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
factor XIII -> factor XIII cleaved tetramer + 2 factor XIII A activation peptides (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
thrombin:antithrombin III:heparin -> thrombin:cleaved antithrombin III:heparin (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
thrombin:SERPINC1:SERPINC1 activators [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
thrombin:cleaved SERPINC1:SERPINC1 activators [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
thrombin:cleaved SERPINC1:SERPINC1 activators -> thrombin:cleaved SERPINC1 + SERPINC1 activators (Mus musculus)
thrombin:cleaved SERPINC1:SERPINC1 activators [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
Intrinsic Pathway of Fibrin Clot Formation (Mus musculus)
factor VIII:von Willibrand factor multimer -> factor VIIIa + factor VIIIa B A3 acidic polypeptide + von Willibrand factor multimer (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
factor XI:platelet glycoprotein (GP) Ib:IX:V complex -> factor XIa:platelet glycoprotein (GP) Ib:IX:V complex (thrombin catalyst) (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 6
Ca2+ [plasma membrane]
F2 [plasma membrane]
(Mus musculus)
F2 [plasma membrane]
(Mus musculus)
Participates
as an input of
Protease nexin-1 (PN1) is a specific and extremely efficient inhibitor of thrombin (Mus musculus)
as a component of
thrombin:cleaved SERPINC1:SERPINC1 activators [plasma membrane] (Mus musculus)
thrombin:SERPINC1:SERPINC1 activators [plasma membrane] (Mus musculus)
activated thrombin:thrombomodulin [plasma membrane] (Mus musculus)
SERPINE2:GAG:activated thrombin (factor IIa) [plasma membrane] (Mus musculus)
Inferred From
activated thrombin (factor IIa) [plasma membrane]
(Homo sapiens)
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