Reactome | Hif1a [cytosol]

Hif1a [cytosol]

Stable Identifier

R-MMU-1234110

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

HN-HIF1A, Q61221

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q61221

Gene Names

Hif1a

Reference Genes

BioGPS Gene:15251 Hif1a

ENSEMBL:ENSMUSG00000021109

ENSEMBL:ENSMUSG00000021109 Hif1a

KEGG Gene (Mus musculus):15251 Hif1a

Monarch:15251 Hif1a

NCBI Gene:15251 Hif1a

UCSC:Q61221 Hif1a

Reference Transcript

Other Identifiers

10396421

1416035_at

1427418_a_at

1448183_a_at

15251

17276328

4402791

4424137

4468427

4535487

4560431

4567732

4568479

4585650

4677363

4742858

4857509

4869905

5002059

5044763

5274269

5279833

5371485

5397232

5400742

5458322

5482022

98628_f_at

98629_f_at

GE42629

GO:0003674

GO:0003700

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0006355

GO:0008150

GO:0009058

GO:0034641

GO:0043226

GO:0046983

ILMN_2689215

ILMN_2852034

af003695_s_at

mMR028348

Participates

as a member of

hydroxyAsn-HIF1A,HIF2A [cytosol] (Mus musculus)

Other forms of this molecule

Hif1a [nucleoplasm]

Hif1a [cytosol]

phospho-Hif1a [cytosol]

Hif1a [cytosol]

Hif1a [nucleoplasm]

Inferred From

HN-HIF1A [cytosol] (Homo sapiens)

Modified Residues

Name

monohydroxylated asparagine at 803 (in Homo sapiens)

Coordinate

803

PsiMod Name

monohydroxylated asparagine

PsiMod Definition

A protein modification that effectively converts an L-asparagine residue to one of the diastereomeric 3-hydroxy-L-asparagine residues.

Cross References

RefSeq

NP_001300848.1, NP_001300849.1, XP_017170450.1, NP_034561.2

ZINC - Substances

HIF1A_MOUSE

Ensembl

ENSMUST00000021530, ENSMUSG00000021109, ENSMUSP00000021530

ZINC target

Q61221

PRO

Q61221

ZINC - Predictions - Purchasable

HIF1A_MOUSE

MGI

106918

PDB

4ZPR

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53762	1	Arnt [nucleoplasm] (R-MMU-1234098)	0.623	5
UniProt:P25233 NECD			0.508	2
UniProt:P35583 Foxa2	1	hnf3-beta/foxa2 [nucleoplasm] (R-MMU-187321)	0.499	5
UniProt:Q09472 EP300	5	Foxo4-S-S-EP300 [nucleoplasm] (R-HSA-9617720) SUMO1-K1020,1024-EP300 [nucleoplasm] (R-HSA-3899306) FOXO4-S-S-EP300 [nucleoplasm] (R-HSA-9617691) p-S,T-EP300 [nucleoplasm] (R-HSA-8878072) EP300 [nucleoplasm] (R-HSA-381325)	0.499	2
UniProt:P40337 VHL	3	VHL [nucleoplasm] (R-HSA-1234127) SUMO1-K159,171,196-VHL [nucleoplasm] (R-HSA-4551697) VHL [cytosol] (R-HSA-391423)	0.499	3
UniProt:P63166 Sumo1	97	Sumo1 [nucleoplasm] (R-MMU-4551623) Sumo1 [nucleoplasm] (R-MMU-4085334) Sumo1 [nucleoplasm] (R-MMU-3968375) Sumo1 [nuclear envelope] (R-MMU-4551627) Sumo1 [nucleoplasm] (R-MMU-4551713) Sumo1 [nucleoplasm] (R-MMU-3730829) Sumo1 [nucleoplasm] (R-MMU-4086096) Sumo1 [nucleoplasm] (R-MMU-4086019) Ncor2-G97-Sumo1 [nucleoplasm] (R-MMU-3927943) Sumo1 [nucleoplasm] (R-MMU-3900210) Sumo1 [nucleoplasm] (R-MMU-4085344) K999-Crebbp-G97-Sumo1 [nucleoplasm] (R-MMU-3927909) K1034-Crebbp-G97-Sumo1 [nucleoplasm] (R-MMU-3927811) K1057-Crebbp-G97-Sumo1 [nucleoplasm] (R-MMU-3927832) Sumo1 [nucleoplasm] (R-MMU-4086067) Sumo1 [nucleoplasm] (R-MMU-3900212) Sumo1 [nucleoplasm] (R-MMU-3927863) Sumo1 [nucleoplasm] (R-MMU-3899290) Sumo1 [nucleoplasm] (R-MMU-3730764) Sumo1 [nucleoplasm] (R-MMU-4085364) Sumo1 [nucleoplasm] (R-MMU-3900219) Sumo1 [nucleoplasm] (R-MMU-4086012) Sumo1 [nucleoplasm] (R-MMU-4086058) Ppargc1a-G97-Sumo1 [nucleoplasm] (R-MMU-3903024) Sumo1 [nucleoplasm] (R-MMU-4090362) Sumo1 [nucleoplasm] (R-MMU-4085278) Sumo1 [nucleoplasm] (R-MMU-4090332) Sumo1 [nucleoplasm] (R-MMU-3730875) Sumo1 [cytosol] (R-MMU-4755505) Sumo1 [nucleoplasm] (R-MMU-4755408) Sumo1 [nucleoplasm] (R-MMU-4755531) Sumo1 [nucleoplasm] (R-MMU-4656987) Aurka-G97-Sumo1 [cytosol] (R-MMU-4655435) Sumo1 [nucleoplasm] (R-MMU-4641311) Sumo1 [nucleoplasm] (R-MMU-4641306) Top2a-Sumo1 [nucleoplasm] (R-MMU-5228507) Sumo1 [nucleoplasm] (R-MMU-4641341) Sumo1 [nucleoplasm] (R-MMU-4615836) Sumo1 [nucleoplasm] (R-MMU-4570527) Sumo1 [nucleoplasm] (R-MMU-3826645) Sumo1 [nucleoplasm] (R-MMU-3826574) Sumo1 [nucleoplasm] (R-MMU-4568857) Sumo1 [nucleoplasm] (R-MMU-4568869) Sumo1 [nucleoplasm] (R-MMU-3730884) Sumo1 [nucleoplasm] (R-MMU-4551625) Sumo1 [nucleoplasm] (R-MMU-4568845) Sumo1 [nucleoplasm] (R-MMU-4551631) Sumo1 [nucleoplasm] (R-MMU-4570452) Sumo1 [nucleoplasm] (R-MMU-4551682) Sumo1 [nucleoplasm] (R-MMU-3730794) Sumo1 [nucleoplasm] (R-MMU-3730735) Sumo1 [nucleoplasm] (R-MMU-4341090) Sumo1 [nucleoplasm] (R-MMU-4755424) Sumo1 [nucleoplasm] (R-MMU-4090321) Sumo1 [nucleoplasm] (R-MMU-4341057) Sumo1 [nucleoplasm] (R-MMU-4719434) Sumo1 [nucleoplasm] (R-MMU-4341020) Sumo1 [nucleoplasm] (R-MMU-4546379) Nr2c1-G97-Sumo1 [nucleoplasm] (R-MMU-4717515) Sumo1 [nucleoplasm] (R-MMU-4090359) Sumo1 [nucleoplasm] (R-MMU-4341056) Sumo1 [nucleoplasm] (R-MMU-4755434) Pparg-G97-Sumo1 [nucleoplasm] (R-MMU-4717484) K395-Pparg-G97-Sumo1 [nucleoplasm] (R-MMU-4717503) Sumo1 [nucleoplasm] (R-MMU-4341069) Sumo1 [nucleoplasm] (R-MMU-4719410) Sumo1 [nucleoplasm] (R-MMU-4719426) Sumo1 [nucleoplasm] (R-MMU-4570544) Sumo1 [nucleoplasm] (R-MMU-3730731) Sumo1 [nucleoplasm] (R-MMU-3730646) Sumo1 [nucleoplasm] (R-MMU-3730738) Sumo1 [nucleoplasm] (R-MMU-3968396) Sumo1 [nucleoplasm] (R-MMU-4570515) Sumo1 [nucleoplasm] (R-MMU-4570462) Sumo1 [nucleoplasm] (R-MMU-4655444) Dnmt3a-G97-Sumo1 [nucleoplasm] (R-MMU-4655380) Sumo1 [nucleoplasm] (R-MMU-4655358) K-Cbx5-G97-Sumo1 [nucleoplasm] (R-MMU-4615850) K84-Cbx5-G97-Sumo1 [nucleoplasm] (R-MMU-4615953) Sumo1 [nucleoplasm] (R-MMU-4551761) Sumo1 [nucleoplasm] (R-MMU-3730622) Sumo1 [nucleoplasm] (R-MMU-3730616) Sumo1 [nucleoplasm] (R-MMU-877304) Sumo1 [nucleoplasm] (R-MMU-2990831) Sumo1 [nucleoplasm] (R-MMU-3730796) Sumo1 [cytosol] (R-MMU-4656941) Sumo1 [nucleoplasm] (R-MMU-3730823) Sumo1 [nucleoplasm] (R-MMU-4551654) Sumo1 [nucleoplasm] (R-MMU-4570549) Sumo1 [nucleoplasm] (R-MMU-8956370) Sumo1 [nucleoplasm] (R-MMU-4615956) Sumo1 [nucleoplasm] (R-MMU-4615877) Sumo1 [nucleoplasm] (R-MMU-4615961) Sumo1 [nucleoplasm] (R-MMU-4616032) Sumo1 [nucleoplasm] (R-MMU-4551756) Sumo1 [nucleoplasm] (R-MMU-4616028) Ube2i-G97-Sumo1 [nucleoplasm] (R-MMU-3730634)	0.463	6

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