Reactome | GLYAT-like proteins transfer glycine to phenylacetyl-CoA

GLYAT-like proteins transfer glycine to phenylacetyl-CoA

Stable Identifier

R-HSA-9971063

Type

Reaction [transition]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

an acyl-CoA + glycine => an N-acylglycine + CoA + H(+)

ReviewStatus

5/5

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Glycine N-acyltransferase GLYAT (Mawal & Qureshi, 1994) and possibly GLYAT-like proteins transfer glycine to phenylacetyl-CoA to form N-phenylacetylglycine (Matsuo et al., 2012).

Literature References

PubMed ID	Title	Journal	Year
7802672	Purification to homogeneity of mitochondrial acyl coa:glycine n-acyltransferase from human liver Mawal, YR, Qureshi, IA	Biochem Biophys Res Commun	1994
22475485	Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma Matsuo, M, Terai, K, Kameda, N, Matsumoto, A, Kurokawa, Y, Funase, Y, Nishikawa, K, Sugaya, N, Hiruta, N, Kishimoto, T	Biochem Biophys Res Commun	2012