Biofilm formation

Stable Identifier
R-HSA-9931953
Type
Pathway
Species
Homo sapiens
Related Species
Escherichia coli
ReviewStatus
3/5
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Biofilm formation
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Irreversible attachment of E.coli to host and other surfaces is the prerequisite for the change of the motile to a sedentary phenotype. This in turn is followed by the production of a complex mature biofilm, resulting in increased resistance towards host defenses and antimicrobial agents. In the last stage, biofilms support the release of new motile bacteria. The biofilm matrix mainly consists of polysaccharides like cellulose and colanic acid, held together by specific adhesins like curlin and Ag43 (reviewed by Van Houdt & Michiels, 2005; Laverty et al., 2014; Rossi et al., 2017).
Literature References
PubMed ID Title Journal Year
28485690 "It's a gut feeling" - Escherichia coli biofilm formation in the gastrointestinal tract environment

Rossi, E, Cimdins, A, Lüthje, P, Brauner, A, Sjöling, Å, Landini, P, Römling, U

Crit Rev Microbiol 2018
25438014 Biomolecular Mechanisms of Pseudomonas aeruginosa and Escherichia coli Biofilm Formation

Laverty, G, Gorman, SP, Gilmore, BF

Pathogens 2014
15950122 Role of bacterial cell surface structures in Escherichia coli biofilm formation

Van Houdt, R, Michiels, CW

Res Microbiol 2005
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Event Information
Go Biological Process
biofilm formation (0042710)
Disease
Cross References
Mondo
Authored
Stephan, R  (2024-12-14)
Created
Stephan, R  (2024-12-14)
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