Attachment of bacteria to epithelial cells

Stable Identifier
R-HSA-9638630
Type
Pathway
Species
Homo sapiens
Related Species
Escherichia coli, Klebsiella pneumoniae
ReviewStatus
3/5
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Physical removal of bacteria from the epithelium is an effective strategy used by the host. It is countered by colonizing bacteria using adhesins that reside on their surface or on pili. Adhesins are the main virulence factors of pathogenic enterobacteria that cause intestinal, bronchial, and urogenital infections (Livrelli et al. 1996, Chahales & Thanassi 2015).
Literature References
PubMed ID Title Journal Year
8818891 Adhesive properties and antibiotic resistance of Klebsiella, Enterobacter, and Serratia clinical isolates involved in nosocomial infections

Livrelli, V, De Champs, C, Di Martino, P, Darfeuille-Michaud, A, Forestier, C, Joly, B

J. Clin. Microbiol. 1996
36949030 E. coli Common pili promote the fitness and virulence of a hybrid aEPEC/ExPEC strain within diverse host environments

Munhoz, DD, Richards, AC, Santos, FF, Mulvey, MA, Piazza, RMF

Gut Microbes 2023
26542038 Structure, Function, and Assembly of Adhesive Organelles by Uropathogenic Bacteria

Chahales, P, Thanassi, DG

Microbiol Spectr 2015
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