Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
Stable Identifier
R-HSA-9930709
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell-Cell communication (Homo sapiens)
Cell junction organization (Homo sapiens)
Cell-cell junction organization (Homo sapiens)
Adherens junctions interactions (Homo sapiens)
Regulation of Homotypic Cell-Cell Adhesion (Homo sapiens)
Regulation of Expression and Function of Type I Classical Cadherins (Homo sapiens)
Regulation of CDH1 Expression and Function (Homo sapiens)
Regulation of CDH1 Gene Transcription (Homo sapiens)
Negative Regulation of CDH1 Gene Transcription (Homo sapiens)
ZEB1 recruits TLE1 and HDAC1/2 to CDH1 gene promoter (Homo sapiens)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm] (Homo sapiens)
ZEB1 represses CDH1 gene transcription (Homo sapiens)
ZEB1:CDH1 gene, SMARCA4:ZEB1:CDH1 gene, HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene, (SETD8:ZEB1:CDH1 gene, SIRT1:MPHOSPH8:ZEB1:CDH1 gene) [nucleoplasm] (Homo sapiens)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm] (Homo sapiens)
Participants
components
HDAC1,(HDAC2) dimers [nucleoplasm]
(Homo sapiens)
TLE1 tetramer [nucleoplasm]
(Homo sapiens)
ZEB1:CDH1 gene [nucleoplasm]
(Homo sapiens)
Participates
as an output of
ZEB1 recruits TLE1 and HDAC1/2 to CDH1 gene promoter (Homo sapiens)
as a member of
ZEB1:CDH1 gene, SMARCA4:ZEB1:CDH1 gene, HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene, (SETD8:ZEB1:CDH1 gene, SIRT1:MPHOSPH8:ZEB1:CDH1 gene) [nucleoplasm] (Homo sapiens)
Inferred To
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Bos taurus)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Caenorhabditis elegans)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Canis familiaris)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Drosophila melanogaster)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Gallus gallus)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Mus musculus)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Rattus norvegicus)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Sus scrofa)
HDAC1,(HDAC2):TLE1:ZEB1:CDH1 gene [nucleoplasm]
(Xenopus tropicalis)
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text
