C binds EXOC1

Stable Identifier
R-HSA-9921319
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Dengue virus type 2
Compartment
cytosol
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
C binds EXOC1
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
DENV C protein binds Exocyst complex component 1 (EXOC1, SEC3, hSc3p), inhibiting its antiviral activity by accelerating its proteasomal degradation. This result was obtained from experiments with the Dengue serotype-2 (DENV-2) NG-C strain (Bhuvanakantham & Ng, 2013).
Literature References
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
dengue disease DOID:12205 breakbone fever, Dengue Fever, classic dengue
Cross References
Mondo
Authored
Stephan, R  (2024-09-08)
Reviewed
Roque Ascenção, F  (2025-10-29)
Mansur, DS  (2025-10-29)
Created
Stephan, R  (2024-09-09)
Cite Us!