BlaSHV-12 hydrolyzes cephalothin

Stable Identifier
R-HSA-9911519
Type
Reaction [transition]
Species
Homo sapiens
Related Species
Klebsiella pneumoniae
Compartment
cytosol
ReviewStatus
3/5
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BlaSHV-12 hydrolyzes cephalothin
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BlaSHV-12 is a common plasmid-encoded extended spectrum beta-lactamase in Klebsiella and other enterobacteria that is able to hydrolyse penicillins and cephalosporins like cephalothin (Nüesch-Inderbinen et al 1997, Kim et al. 1998).
Literature References
PubMed ID Title Journal Year
9145849 Survey and molecular genetics of SHV beta-lactamases in Enterobacteriaceae in Switzerland: two novel enzymes, SHV-11 and SHV-12

Nüesch-Inderbinen, MT, Kayser, FH, Hächler, H

Antimicrob. Agents Chemother. 1997
9574728 Survey of Klebsiella pneumoniae strains producing extended-spectrum beta-lactamases: prevalence of SHV-12 and SHV-2a in Korea

Kim, J, Kwon, Y, Pai, H, Kim, JW, Cho, DT

J. Clin. Microbiol. 1998
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Catalyst Activity

beta-lactamase activity of BlaSHV-12 [cytosol]

Physical Entity
BlaSHV-12 [cytosol] (Klebsiella pneumoniae)
Activity
beta-lactamase activity (GO:0008800)
Disease
Cross References
RHEA
Mondo
Authored
Stephan, R  (2019-02-19)
Created
Stephan, R  (2024-06-01)
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