Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14

Stable Identifier
R-HSA-9907998
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol
ReviewStatus
3/5
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Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14
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Components of the proteasome 19S regulatory particle (19S RP) lid PSMD7 (ortholog of yeast Rpn8), PSMD12 (ortholog of yeast Rpn5), PSMD13 (ortholog of yeast Rpn9), and PSMD14 (ortholog of yeast Rpn11) bind to each other (reviewed in Tomko and Hochstrasser 2013). In human embryonic kidney cell line HEK293T, it was confirmed that human PSMD12 (Rpn5), PSMD7 (Rpn8), PSMD13 (Rpn9), and PSMD14 (Rpn11) form a complex (Bai et al. 2019). PSMD14 (Rpn11) is not required for the formation of a heterotrimer between PSMD12 (Rpn5), PSMD7 (Rpn8) and PSMD13 (Rpn9) (Bai et al. 2019).
Literature References
PubMed ID Title Journal Year
31159305 In-depth Analysis of the Lid Subunits Assembly Mechanism in Mammals

Bai, M, Zhao, X, Sahara, K, Ohte, Y, Hirano, Y, Kaneko, T, Yashiroda, H, Murata, S

Biomolecules 2019
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Orthologous Events
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Bos taurus)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Caenorhabditis elegans)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Danio rerio)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Dictyostelium discoideum)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Drosophila melanogaster)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Gallus gallus)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Mus musculus)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Plasmodium falciparum)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Rattus norvegicus)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Saccharomyces cerevisiae)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Schizosaccharomyces pombe)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Sus scrofa)
Formation of the complex of PSMD7, PSMD12, PSMD13, and PSMD14 (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2024-04-22)
Created
Orlic-Milacic, M  (2024-04-18)
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