Binding of SP1 to TGFBR3 gene promoter

Stable Identifier
R-HSA-9860130
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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Binding of SP1 to TGFBR3 gene promoter
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TGFBR3 promoter contains several GC box, Sp1 binding sequences with several possible transcription start sites. (Ji et al, 1999 and Lopez-Casillas et al, 2003). Sp1 region is conserved in the TGBFR3 promoter region in both humans and mice. (Hempel et al, 2008).
Literature References
PubMed ID Title Journal Year
10521429 Cloning the promoter for transforming growth factor-beta type III receptor. Basal and conditional expression in fetal rat osteoblasts

Ji, C, Chen, Y, McCarthy, TL, Centrella, M

J Biol Chem 1999
12399463 Betaglycan expression is transcriptionally up-regulated during skeletal muscle differentiation. Cloning of murine betaglycan gene promoter and its modulation by MyoD, retinoic acid, and transforming growth factor-beta

López-Casillas, F, Riquelme, C, Perez-Kato, Y, Ponce-Castaneda, MV, Osses, N, Esparza-Lopez, J, Gonzalez-Nunez, G, Cabello-Verrugio, C, Mendoza, V, Troncoso, V, Brandan, E

J Biol Chem 2003
18299279 Expression of the type III TGF-beta receptor is negatively regulated by TGF-beta

Hempel, N, How, T, Cooper, SJ, Green, TR, Dong, M, Copland, JA, Wood, CG, Blobe, GC

Carcinogenesis 2008
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2024-01-31)
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