TGFBR3 expression

Stable Identifier
R-HSA-9839394
Type
Pathway
Species
Homo sapiens
ReviewStatus
3/5
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TGFBR3 expression
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This pathway describes the transcriptional and translational regulation of TGFBR3. Regulation of TGFBR3 expression includes different transcription factors (Sp1, MyoD and RAR) (Lopez-Casillas et al., 2003), epigenetic regulators such as HELLS (Hou et al., 2021) and KLP16 (Chen et al., 2022)), and translational regulation by miRNAs (Wang et al., 2019, Zhu et al., 2012).
Literature References
PubMed ID Title Journal Year
22660635 The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-α

Wang, H, Harley, JB, Liu, Y, Zhu, S, Pan, W, Song, X, Shen, N, Shi, Y, Liu, W, Shao, X, He, D, Liang, D, Tang, Y, Qian, Y

Nat. Med. 2012
30467960 MicroRNA let-7a regulates angiogenesis by targeting TGFBR3 mRNA

Chen, C, Wu, D, Xiang, Y, Ni, H, Zhou, H, Wang, S, Dai, K, Chen, X, Chen, Z, Li, X

J Cell Mol Med 2019
33280236 HELLS, a chromatin remodeler is highly expressed in pancreatic cancer and downregulation of it impairs tumor growth and sensitizes to cisplatin by reexpressing the tumor suppressor TGFBR3

Kong, F, Zhou, Y, He, J, Wang, K, Liu, X, Li, Q, Yang, L, Hou, X

Cancer Med 2021
35173481 KLF16 Downregulates the Expression of Tumor Suppressor Gene TGFBR3 to Promote Bladder Cancer Proliferation and Migration

Chen, X, Wang, P, Ou, T, Li, J

Cancer Manag Res 2022
12399463 Betaglycan expression is transcriptionally up-regulated during skeletal muscle differentiation. Cloning of murine betaglycan gene promoter and its modulation by MyoD, retinoic acid, and transforming growth factor-beta

Cabello-Verrugio, C, Mendoza, V, Osses, N, Gonzalez-Nunez, G, Ponce-Castaneda, MV, Brandan, E, Riquelme, C, López-Casillas, F, Perez-Kato, Y, Esparza-Lopez, J, Troncoso, V

J Biol Chem 2003
Participants
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Authored
Tiwari, K  (2023-07-25)
Created
Tiwari, K  (2023-07-05)
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