Reactome | corneocyte

Stable Identifier

R-HSA-9855603

Type

Cell

Species

Homo sapiens

Locations in the PathwayBrowser

Expand all

Cytology

Organ

skin of body (UBERON:0002097)

Tissue

skin epidermis (UBERON:0001003)

Tissue Layer

stratum corneum of epidermis (UBERON:0002027)

Cell Type

corneocyte (CL:0002153)

Markers

Protein

- Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation.J Invest Dermatol134,2938-2946(2014)Simon, M., Serre, G., Malaisse, J., Paul, C., Kezic, S., Poumay, Y., Le Lamer, M., Schmitt, AM., Pellerin, L., Pendaries, V., Nachat, R.
- PanglaoDB: a web server for exploration of mouse and human single-cell RNA sequencing data.Database (Oxford)2019,null(2019)Franzén, O., Gan, LM., Björkegren, JLM.
- Normal human epidermal keratinocytes express in vitro specific molecular forms of (pro)filaggrin recognized by rheumatoid arthritis-associated antifilaggrin autoantibodies.Mol Med3,145-56(1997)Sebbag, M., Montézin, M., Girbal-Neuhauser, E., Serre, G., Durieux, JJ., Simon, M., Croute, F.
- Evidence that filaggrin is a component of cornified cell envelopes in human plantar epidermis.Biochem J317,173-7(1996)Schmitt, D., Montézin, M., Sebbag, M., Girbal-Neuhauser, E., Serre, G., Simon, M., Haftek, M.

- Ultrastructural localization of caspase-14 in human epidermis.J Histochem Cytochem52,1561-74(2004)Dockal, M., Alibardi, L., Reinisch, C., Eckhart, L., Tschachler, E.
- Stratum corneum-derived caspase-14 is catalytically active.FEBS Lett577,446-50(2004)Stichenwirth, M., Dockal, M., Kapetanopoulos, A., Ghannadan, M., Buchberger, M., Eckhart, L., Fischer, H., Declercq, W., Bach, J., Tschachler, E.

- Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7.J Invest Dermatol122,1235-44(2004)Simon, M., Serre, G., Guerrin, M., Brattsand, M., Bernard, D., Egelrud, T., Schmidt, R., Caubet, C., Jonca, N.
- Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation.J Invest Dermatol134,1665-1674(2014)Miyai, M., Tsuboi, R., Yamanishi, H., Matsumoto, Y., Hibino, T., Yamamoto-Tanaka, M.
- Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.J Invest Dermatol137,430-439(2017)Hovnanian, A., Munro, CA., Furio, L., Swedberg, JE., Brattsand, M., de Veer, SJ., Harris, JM., Clements, JA.

- Degradation of corneodesmosome proteins by two serine proteases of the kallikrein family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7.J Invest Dermatol122,1235-44(2004)Simon, M., Serre, G., Guerrin, M., Brattsand, M., Bernard, D., Egelrud, T., Schmidt, R., Caubet, C., Jonca, N.
- Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum.J Invest Dermatol137,430-439(2017)Hovnanian, A., Munro, CA., Furio, L., Swedberg, JE., Brattsand, M., de Veer, SJ., Harris, JM., Clements, JA.

- Ultrastructural localization of caspase-14 in human epidermis.J Histochem Cytochem52,1561-74(2004)Dockal, M., Alibardi, L., Reinisch, C., Eckhart, L., Tschachler, E.
- Stratum corneum-derived caspase-14 is catalytically active.FEBS Lett577,446-50(2004)Stichenwirth, M., Dockal, M., Kapetanopoulos, A., Ghannadan, M., Buchberger, M., Eckhart, L., Fischer, H., Declercq, W., Bach, J., Tschachler, E.

Participates

as an output of