FUT1,2 transfer fucose to gangliosides

Stable Identifier
R-HSA-9846332
Type
Reaction [transition]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
Locations in the PathwayBrowser
General
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Galactoside 2-α-L-fucosyltransferase 1 and 2 (FUT1,2 aka α-1,2-fucosyltransferase 1,2) transfer a fucose (Fuc) sugar to the galactose (Gal) sugar of gangliosides GA1 and GM1 to form FucGA1 and FucGM1, but also the equivalent derivatives of glycoproteins (H antigen; Larsen et al. 1990; Kelly et al., 1995).
Participants
Participates
Catalyst Activity

fucosyltransferase activity of FUT1,2 [Golgi membrane]

Orthologous Events
Cross References
Rhea
Authored
Reviewed
Created
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