Reactome | CLPX [mitochondrial matrix]

CLPX [mitochondrial matrix]

Stable Identifier

R-HSA-9838010

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O76031 CLPX

Gene Names

CLPX

Chain

transit peptide:1-56, chain:57-633

Reference Genes

BioGPS Gene:10845 CLPX

COSMIC (genes):CLPX CLPX

CTD Gene:10845 CLPX

dbSNP Gene:10845 CLPX

ENSEMBL:ENSG00000166855 CLPX

HGNC:2088 CLPX

KEGG:hsa:10845 CLPX

Monarch:10845 CLPX

NCBI Gene:10845 CLPX

OMIM:615611 CLPX

UCSC:O76031 CLPX

Reference Transcript

RefSeq:NM_006660.4 CLPX

Other Identifiers

10845

11740676_a_at

11763746_a_at

11763747_x_at

11763757_a_at

11763988_a_at

16810686

204809_PM_at

204809_at

223507_PM_at

223507_at

3629493

3629495

3629496

3629497

3629498

3629499

3629500

3629501

3629502

3629503

3629504

3629505

3629506

3629508

3629509

3629510

3629511

3629512

3629513

3629514

3629515

3629516

3629519

3629521

3629523

3629524

3629525

3629528

37453_at

48588_at

7989735

A_23_P140511

A_24_P171041

GE55169

GO:0000166

GO:0004176

GO:0005515

GO:0005524

GO:0005654

GO:0005739

GO:0005743

GO:0005759

GO:0005829

GO:0006457

GO:0006508

GO:0008270

GO:0009368

GO:0009841

GO:0016504

GO:0016787

GO:0016887

GO:0042645

GO:0046034

GO:0046872

GO:0046983

GO:0051082

GO:0051603

GO:0055086

GO:0098772

GO:0140657

GO:0140662

GO:1901135

HMNXSV003013552

ILMN_1709894

PH_hs_0006253

PH_hs_0035534

TC15001561.hg

g12053338_3p_at

g12597621_3p_at

Participates

as a component of

CLPXP [mitochondrial matrix] (Homo sapiens)

Inferred To

CLPX [mitochondrial matrix] (Bos taurus)

CLPX [mitochondrial matrix] (Caenorhabditis elegans)

CLPX [mitochondrial matrix] (Canis familiaris)

CLPX [mitochondrial matrix] (Sus scrofa)

Clpx [mitochondrial matrix] (Mus musculus)

Clpx [mitochondrial matrix] (Rattus norvegicus)

ClpX [mitochondrial matrix] (Drosophila melanogaster)

clpx [mitochondrial matrix] (Xenopus tropicalis)

clpxb [mitochondrial matrix] (Danio rerio)

Cross References

RefSeq

NP_006651.2

ENSEMBL

ENSG00000166855, ENSP00000300107, ENST00000300107

OpenTargets

ENSG00000166855

GeneCards

CLPX

HPA

ENSG00000166855-CLPX

PRO

O76031

Pharos - Targets

O76031

GlyGen

O76031

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P47985 UQCRFS1	3	UQCRFS1(1-274) [mitochondrial inner membrane] (R-HSA-9906005) UQCRFS1(1-274) [mitochondrial matrix] (R-HSA-9906006) UQCRFS1(79-274) [mitochondrial inner membrane] (R-HSA-164278)	0.527	2
UniProt:Q9Y297 BTRC	2	BTRC [cytosol] (R-HSA-174237) BTRC [nucleoplasm] (R-HSA-3361753)	0.527	3