Reactome | CLPX [mitochondrial matrix]

CLPX [mitochondrial matrix]

Stable Identifier

R-HSA-9838010

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial, CLPX_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O76031 CLPX

Gene Names

CLPX

Chain

transit peptide:1-56, chain:57-633

Reference Genes

BioGPS Gene:10845 CLPX

COSMIC (genes):CLPX CLPX

CTD Gene:10845 CLPX

dbSNP Gene:10845 CLPX

ENSEMBL:ENSG00000166855 CLPX

HGNC:2088 CLPX

Monarch:10845 CLPX

NCBI Gene:10845 CLPX

OMIM:615611 CLPX

UCSC:O76031 CLPX

Reference Transcript

RefSeq:NM_006660.4 CLPX

Other Identifiers

10845

11740676_a_at

11763746_a_at

11763747_x_at

11763757_a_at

11763988_a_at

16810686

204809_PM_at

204809_at

223507_PM_at

223507_at

3629493

3629495

3629496

3629497

3629498

3629499

3629500

3629501

3629502

3629503

3629504

3629505

3629506

3629507

3629508

3629509

3629510

3629511

3629512

3629513

3629514

3629515

3629516

3629519

3629521

3629523

3629524

3629525

3629528

37453_at

48588_at

7989735

A_23_P140511

A_24_P171041

GE55169

GO:0003824

GO:0004176

GO:0005515

GO:0005524

GO:0005654

GO:0005739

GO:0005743

GO:0005759

GO:0005829

GO:0006457

GO:0006508

GO:0008270

GO:0009368

GO:0009841

GO:0016504

GO:0016787

GO:0016887

GO:0042645

GO:0043226

GO:0044183

GO:0046034

GO:0046872

GO:0046983

GO:0051082

GO:0051603

GO:0055086

GO:0098772

GO:0140096

GO:0140657

GO:0140662

GO:1901135

HMNXSV003013552

ILMN_1709894

PH_hs_0006253

PH_hs_0035534

TC15001561.hg

g12053338_3p_at

g12597621_3p_at

Participates

as a component of

CLPXP [mitochondrial matrix] (Homo sapiens)

Inferred To

CLPX [mitochondrial matrix] (Bos taurus)

CLPX [mitochondrial matrix] (Caenorhabditis elegans)

CLPX [mitochondrial matrix] (Canis familiaris)

CLPX [mitochondrial matrix] (Mus musculus)

CLPX [mitochondrial matrix] (Rattus norvegicus)

CLPX [mitochondrial matrix] (Sus scrofa)

ClpX [mitochondrial matrix] (Drosophila melanogaster)

clpx [mitochondrial matrix] (Xenopus tropicalis)

Cross References

ENSEMBL

ENSP00000300107, ENST00000300107

OpenTargets

ENSG00000166855

HPA

ENSG00000166855-CLPX

PRO

O76031

Pharos - Targets

O76031

GlyGen

O76031

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P15586 GNS	10	GNS [Golgi lumen] (R-HSA-434323) GNS [lysosomal lumen] (R-HSA-434208) GNS Q390* [lysosomal lumen] (R-HSA-2245231) GNS Q272* [lysosomal lumen] (R-HSA-2245247) GNS S94I [lysosomal lumen] (R-HSA-2245243) GNS R355* [lysosomal lumen] (R-HSA-2245238) OxA-GNS [lysosomal lumen] (R-HSA-1638063) GNS [ficolin-1-rich granule lumen] (R-HSA-6800961) GNS [extracellular region] (R-HSA-6806208) GNS [azurophil granule lumen] (R-HSA-6799222)	0.527	2
UniProt:Q9Y297 BTRC	2	BTRC [cytosol] (R-HSA-174237) BTRC [nucleoplasm] (R-HSA-3361753)	0.527	3