Reactome | UQCRFS1(1-274) [mitochondrial matrix]

UQCRFS1(1-274) [mitochondrial matrix]

Stable Identifier

R-HSA-9906006

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

mitochondrial matrix

Synonyms

Full length Rieske protein

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P47985 UQCRFS1

Gene Names

UQCRFS1

Chain

chain:1-78, chain:79-274

Reference Genes

BioGPS Gene:7386 UQCRFS1

COSMIC (genes):UQCRFS1 UQCRFS1

CTD Gene:7386 UQCRFS1

dbSNP Gene:7386 UQCRFS1

ENSEMBL:ENSG00000169021 UQCRFS1

HGNC:12587 UQCRFS1

KEGG:hsa:7386 UQCRFS1

Monarch:7386 UQCRFS1

NCBI Gene:7386 UQCRFS1

OMIM:191327 UQCRFS1

UCSC:P47985 UQCRFS1

Reference Transcript

RefSeq:NM_006003.3 UQCRFS1

Other Identifiers

11757847_s_at

16871051

208909_PM_at

208909_at

34401_at

3857690

3857692

3857693

3857694

3857695

3857696

3857699

3946089

3946091

3946093

3946094

71020_at

7386

8035880

8073192

A_23_P153586

GE60494

GE840777

GO:0003824

GO:0005215

GO:0005515

GO:0005739

GO:0005743

GO:0005759

GO:0006091

GO:0006122

GO:0008121

GO:0016020

GO:0016491

GO:0022904

GO:0034551

GO:0043226

GO:0045275

GO:0046872

GO:0051537

GO:0055085

GO:0065003

GO:1902600

HMNXSV003008829

ILMN_1701749

L32977_at

PH_hs_0027398

TC19001379.hg

g12653726_3p_at

Participates

as a component of

UQCRFS1(1-274):LYRM7 [mitochondrial matrix] (Homo sapiens)

as an input of

apo-UQCRFS1 binds LYRM7 (Homo sapiens)

Other forms of this molecule

UQCRFS1(1-274) [mitochondrial inner membrane]

UQCRFS1(79-274) [mitochondrial inner membrane]

Inferred To

rip1 [mitochondrial matrix] (Schizosaccharomyces pombe)

RFeSP [mitochondrial matrix] (Drosophila melanogaster)

ucr [mitochondrial matrix] (Dictyostelium discoideum)

UQCRFS1 [mitochondrial matrix] (Bos taurus)

UQCRFS1 [mitochondrial matrix] (Canis familiaris)

UQCRFS1 [mitochondrial matrix] (Gallus gallus)

UQCRFS1 [mitochondrial matrix] (Sus scrofa)

Uqcrfs1 [mitochondrial matrix] (Mus musculus)

Uqcrfs1 [mitochondrial matrix] (Rattus norvegicus)

RIP1 [mitochondrial matrix] (Saccharomyces cerevisiae)

uqcrfs1 [mitochondrial matrix] (Danio rerio)

uqcrfs1 [mitochondrial matrix] (Xenopus tropicalis)

Cross References

RefSeq

NP_005994.2

ENSEMBL

ENSP00000306397, ENST00000304863, ENSG00000169021

OpenTargets

ENSG00000169021

IntEnz

7.1.1.8

GeneCards

UQCRFS1

HPA

ENSG00000169021-UQCRFS1

PRO

P47985

Pharos - Targets

P47985

GlyGen

P47985

Orphanet

UQCRFS1

HMDB Protein

HMDBP00990

PDB

5XTE, 5XTI, 5XTH

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q5U5X0 LYRM7	1	LYRM7 [mitochondrial matrix] (R-HSA-9866252)	0.794	17
UniProt:Q8WUK0 DUSP23	1	PTPMT1 [mitochondrial inner membrane] (R-HSA-3446802)	0.527	4
UniProt:Q96RQ3 MCCC1	9	Btn-MCCC1 [mitochondrial matrix] (R-HSA-70748) MCCC1 [cytosol] (R-HSA-3323164) Btn-MCCC1 [cytosol] (R-HSA-3323154) R385S Btn-MCCC1 [mitochondrial matrix] (R-HSA-9908676) I460M Btn-MCCC1 [mitochondrial matrix] (R-HSA-9908657) M325R Btn-MCCC1 [mitochondrial matrix] (R-HSA-9908669) D532H Btn-MCCC1 [mitochondrial matrix] (R-HSA-9908652) V694* Btn-MCCC1 [mitochondrial matrix] (R-HSA-9908683) L437P Btn-MCCC1 [mitochondrial matrix] (R-HSA-9908666)	0.527	3
UniProt:O76031 CLPX	1	CLPX [mitochondrial matrix] (R-HSA-9838010)	0.527	2
UniProt:P36776 LONP1	1	LONP1 [mitochondrial matrix] (R-HSA-9838000)	0.527	2
UniProt:O14561 NDUFAB1	3	NDUFAB1 [mitochondrial inner membrane] (R-HSA-163925) octanoyl-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-9857608) Mal-PPANT-S112-NDUFAB1 [mitochondrial inner membrane] (R-HSA-8934586)	0.527	3
UniProt:Q8TCS8 PNPT1	1	PNPT1 [mitochondrial matrix] (R-HSA-9836559)	0.527	2
UniProt:Q8TB22 SPT20			0.527	3
UniProt:P22830 FECH	1	FECH [mitochondrial inner membrane] (R-HSA-189441)	0.527	3
UniProt:Q96RP9 GFM1	1	GFM1 [mitochondrial matrix] (R-HSA-5389859)	0.527	2
UniProt:Q6DKK2 TTC19	1	TTC19 [mitochondrial inner membrane] (R-HSA-9906047)	0.527	3
UniProt:Q9H1K1 ISCU	1	ISCU [cytosol] (R-HSA-9771680)	0.462	4
UniProt:P38646 HSPA9	6	HSPA9 [mitochondrial matrix] (R-HSA-8878802) HSPA9 [mitochondrial inner membrane] (R-HSA-1252206) HSPA9(1-679) [cytosol] (R-HSA-1267964) HSPA9(1-679) [mitochondrial intermembrane space] (R-HSA-1267968) HSPA9 [nucleoplasm] (R-HSA-5252128) HSPA9 [cytosol] (R-HSA-5251993)	0.462	4
UniProt:Q8IWL3 HSCB	5	HSCB [mitochondrial matrix] (R-HSA-1299438) HSCB [mitochondrial inner membrane] (R-HSA-1299447) HSCB(1-235) [mitochondrial inner membrane] (R-HSA-1299443) HSCB(1-30) [mitochondrial matrix] (R-HSA-8986120) HSCB(1-235) [mitochondrial intermembrane space] (R-HSA-1299456)	0.462	6

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