Reactome | Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

Stable Identifier

R-HSA-983425

Type

Reaction [binding]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane, cytosol, endoplasmic reticulum lumen

Locations in the PathwayBrowser

Expand all

General

SBML | | PDF

SVG | | PPTX | SBGN

Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

Sec13-Sec31 binds the prebudding complex and this Sec13-Sec31 heterotetramer forms the outer structural scaffold of the coat. Sec13-Sec31 is likely to crosslink the prebudding complexes generating COPII-coated vesicles.

Literature References

PubMed ID	Title	Journal	Year
10982397	Dynamics of transitional endoplasmic reticulum sites in vertebrate cells Hammond, AT, Glick, BS	Mol Biol Cell	2000
10825291	COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites Stephens, DJ, Lin-Marq, N, Pagano, A, Pepperkok, R, Paccaud, JP	J Cell Sci	2000