Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle

Stable Identifier
R-HSA-983425
Type
Reaction
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, cytosol, endoplasmic reticulum lumen
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Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle
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Sec13-Sec31 binds the prebudding complex and this Sec13-Sec31 heterotetramer forms the outer structural scaffold of the coat. Sec13-Sec31 is likely to crosslink the prebudding complexes generating COPII-coated vesicles.

Literature References
PubMed ID Title Journal Year
10825291 COPI-coated ER-to-Golgi transport complexes segregate from COPII in close proximity to ER exit sites

Paccaud, JP, Lin-Marq, N, Stephens, DJ, Pagano, A, Pepperkok, R

J Cell Sci 2000
10982397 Dynamics of transitional endoplasmic reticulum sites in vertebrate cells

Glick, BS, Hammond, AT

Mol Biol Cell 2000
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Orthologous Events
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Canis familiaris)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Danio rerio)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Gallus gallus)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Mus musculus)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Rattus norvegicus)
Recruitment of Sec31p:Sec13p to prebudding complex and formation of COPII vesicle (Sus scrofa)
Authored
Garapati, P V  (2010-10-29)
Reviewed
Elliott, T  (2011-02-10)
Created
Garapati, P V  (2010-11-01)
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