POU3F1 binds the SOX2 gene

Stable Identifier
R-HSA-9832824
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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POU3F1 binds the SOX2 gene
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POU3F1 (OCT6) binds the N2 enhancer located upstream of the SOX2 coding region (inferred from mouse homologs). Before gastrulation, POU5F1 (OCT4) binds the N2 enhancer and SOX2 is expressed throughout the epiblast. POU3F1 replaces POU5F1 at the N2 enhancer in anterior ectoderm and maintains expression in anterior neural plate (inferred from mouse homologs).
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Pou3f1 binds the Sox2 gene (Mus musculus)
Authored
May, B  (2023-04-09)
Reviewed
Kondoh, H  (2023-07-12)
Created
May, B  (2023-04-09)
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