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POU3F1 [nucleoplasm]
Stable Identifier
R-HSA-9613634
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
POU domain, class 3, transcription factor 1, PO3F1_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Formation of the anterior neural plate (Homo sapiens)
Expression of OTX2 in anterior neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:OTX2 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of PAX6 in anterior neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:ZNF521:PAX6 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of POU3F1 in anterior neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of SOX1 in neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of SOX2 in anterior neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:SOX2 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of ZEB2 in neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of ZIC2 in anterior neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:ZIC2 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of ZNF521 in anterior neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:ZNF521 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 and ZNF521 bind the PAX6 gene (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:ZNF521:PAX6 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 binds the OTX2 gene (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:OTX2 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 binds the SOX2 gene (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:SOX2 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 binds the ZIC2 gene (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:ZIC2 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 binds the ZNF521 gene (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1:ZNF521 gene [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Formation of the posterior neural plate (Homo sapiens)
Expression of SOX1 in neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Expression of ZEB2 in neural plate (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
Nervous system development (Homo sapiens)
EGR2 and SOX10-mediated initiation of Schwann cell myelination (Homo sapiens)
EGR2 gene expression (Homo sapiens)
EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
SOX10, POU3F1 and POU3F2 bind EGR2 gene (Homo sapiens)
EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
SOX10-dependent POU3F1 gene expression (Homo sapiens)
POU3F1 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03052 POU3F1
Gene Names
POU3F1, OCT6, OTF6
Chain
chain:1-451
Reference Genes
BioGPS Gene:5453 POU3F1
COSMIC (genes):POU3F1 POU3F1
CTD Gene:5453 POU3F1
dbSNP Gene:5453 POU3F1
ENSEMBL:ENSG00000185668 POU3F1
HGNC:9214 POU3F1
KEGG:hsa:5453 POU3F1
Monarch:5453 POU3F1
NCBI Gene:5453 POU3F1
OMIM:602479 POU3F1
UCSC:Q03052 POU3F1
Reference Transcript
RefSeq:NM_002699.3 POU3F1
Other Identifiers
11734338_at
11734339_at
16685580
208345_PM_s_at
208345_s_at
210475_PM_at
210475_at
2407507
2407508
2407509
2407510
2407511
2407512
2407513
2407514
2407515
2407516
33675_at
5453
7915156
A_23_P97034
A_24_P131293
A_33_P3351052
GE57702
GO:0000785
GO:0000978
GO:0000981
GO:0003677
GO:0003700
GO:0005634
GO:0005654
GO:0005667
GO:0006355
GO:0006357
GO:0007420
GO:0008366
GO:0008544
GO:0010628
GO:0014044
GO:0022011
GO:0030154
GO:0030216
GO:0030900
GO:0042552
GO:0043226
GO:0043565
GO:0045893
GO:0048856
GO:0140110
GO:1990837
HMNXSV003035323
ILMN_2086981
L26494_at
TC01002531.hg
TC01005412.hg
TC01005413.hg
g4505960_3p_a_at
g508989_3p_at
Participates
as a component of
POU3F1:OTX2 gene [nucleoplasm] (Homo sapiens)
POU3F1:SOX2 gene [nucleoplasm] (Homo sapiens)
POU3F1:ZIC2 gene [nucleoplasm] (Homo sapiens)
POU3F1:ZNF521:PAX6 gene [nucleoplasm] (Homo sapiens)
POU3F1:ZNF521 gene [nucleoplasm] (Homo sapiens)
EGR2 gene:POU3F1:POU3F2:SOX10 [nucleoplasm] (Homo sapiens)
as an input of
POU3F1 binds the OTX2 gene (Homo sapiens)
POU3F1 binds the SOX2 gene (Homo sapiens)
POU3F1 binds the ZIC2 gene (Homo sapiens)
POU3F1 and ZNF521 bind the PAX6 gene (Homo sapiens)
POU3F1 binds the ZNF521 gene (Homo sapiens)
SOX10, POU3F1 and POU3F2 bind EGR2 gene (Homo sapiens)
as an output of
Expression of POU3F1 in anterior neural plate (Homo sapiens)
SOX10-dependent POU3F1 gene expression (Homo sapiens)
This entity regulates
Positively
Expression of SOX1 in neural plate
(Homo sapiens)
Expression of ZEB2 in neural plate
(Homo sapiens)
Cross References
ENSEMBL
ENST00000373012
,
ENSP00000362103
,
ENSG00000185668
OpenTargets
ENSG00000185668
GeneCards
POU3F1
HPA
ENSG00000185668-POU3F1
PRO
Q03052
Pharos - Targets
Q03052
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