NS1:NS2 (1C:1B) localizes to mitochondria

Stable Identifier
R-HSA-9832577
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
cytosol, mitochondrial matrix
Synonyms
NS1:NS2 localizes to mitochondria
ReviewStatus
5/5
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NS1:NS2 (1C:1B) localizes to mitochondria
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The 1C:1B (NS1:NS2) complex localizes to the mitochondrial matrix where the 1C (NS1) subunit binds to mitochondrial antiviral signaling protein (MAVS) (Swedan et al, 2011l Boyapalle et al, 2012).
Literature References
PubMed ID Title Journal Year
22383950 Respiratory syncytial virus NS1 protein colocalizes with mitochondrial antiviral signaling protein MAVS following infection

Wong, T, San Juan-Vergara, H, Mohapatra, S, Garay, J, Boyapalle, S, Mohapatra, S, Teng, M

PLoS One 2012
21795342 Multiple functional domains and complexes of the two nonstructural proteins of human respiratory syncytial virus contribute to interferon suppression and cellular location

Andrews, J, Swedan, S, Majumdar, T, Barik, S, Musiyenko, A

J Virol 2011
Participants
Input
Output
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as an event of
Disease
Authored
Stephan, R  (2023-03-30)
Reviewed
Bergeron, HC  (2023-11-03)
Created
Stephan, R  (2023-04-03)
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