NS1 (1C) localizes to nucleus

Stable Identifier
R-HSA-9832169
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
cytosol, nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
NS1 (1C) localizes to nucleus
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
RSV non-structural protein 1C (NS1) localizes to the nucleus where it interacts with the host cell chromatin (Swedan et al, 2011; Pei et al, 2021).
Literature References
PubMed ID Title Journal Year
34644581 Nuclear-localized human respiratory syncytial virus NS1 protein modulates host gene transcription

Pei, J, Beri, NR, Zou, AJ, Hubel, P, Dorando, HK, Bergant, V, Andrews, RD, Pan, J, Andrews, JM, Sheehan, KCF, Pichlmair, A, Amarasinghe, GK, Brody, SL, Payton, JE, Leung, DW

Cell Rep 2021
21795342 Multiple functional domains and complexes of the two nonstructural proteins of human respiratory syncytial virus contribute to interferon suppression and cellular location

Swedan, S, Andrews, J, Majumdar, T, Musiyenko, A, Barik, S

J Virol 2011
Participants
Input
Output
Participates
as an event of
Disease
Cross References
Mondo
Authored
Stephan, R  (2023-03-29)
Reviewed
Bergeron, HC  (2023-11-03)
Created
Stephan, R  (2023-03-29)
Cite Us!