Reactome | NS2 (1B) forms a homodimer

NS2 (1B) forms a homodimer

Stable Identifier

R-HSA-9832168

Type

Reaction [binding]

Species

Homo sapiens

Related Species

Human respiratory syncytial virus A

Compartment

cytosol

ReviewStatus

5/5

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - Respiratory syncytial virus (RSV) genome replication, transcription and translation (Homo sapiens)
        
        Maturation of hRSV A proteins (Homo sapiens)
        
        NS2 (1B) forms a homodimer (Homo sapiens)

General

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RSV non-structural protein 1B (NS2) dimerizes (Evans et al, 1996; Swedan et al, 2011).

Literature References

PubMed ID	Title	Journal	Year
8864205	Expression and characterisation of the NS1 and NS2 proteins of respiratory syncytial virus Evans, JE, Cane, PA, Pringle, CR	Virus Res	1996
21795342	Multiple functional domains and complexes of the two nonstructural proteins of human respiratory syncytial virus contribute to interferon suppression and cellular location Swedan, S, Andrews, J, Majumdar, T, Musiyenko, A, Barik, S	J Virol	2011

Participants

Input

x 2 NS2 [cytosol] (Human respiratory syncytial virus A)

Output

NS2 dimer [cytosol] (Human respiratory syncytial virus A)

Participates

as an event of

Maturation of hRSV A proteins (Homo sapiens)

Disease

Name	Identifier	Synonyms
respiratory syncytial virus infectious disease	DOID:1273

Cross References

Mondo

0001577

Authored

Stephan, R (2023-03-29)

Reviewed

Bergeron, HC (2023-11-03)

Created

Stephan, R (2023-03-29)

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