P binds to PPP1C complex

Stable Identifier
R-HSA-9832037
Type
Reaction [uncertain]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
cytosol
ReviewStatus
5/5
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P binds to PPP1C complex
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Protein P binds to the cellular phosphatase PP1 complex, which recruits it to viral inclusion bodies. Dephosphorylation of protein M2-1, which is catalyzed by a complex formed between P and the PP1 complex, is required, in a cyclic manner, for efficient viral transcription (Richard et al, 2018).
Literature References
PubMed ID Title Journal Year
29489893 RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription

Eléouët, JF, Lassoued, S, Galloux, M, Richard, CA, Cardone, C, Rameix-Welti, MA, Sizun, C, Rincheval, V, Nekhai, S, Fix, J, Esneau, C

PLoS Pathog 2018
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Output
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as an event of
Disease
Authored
Stephan, R  (2023-03-24)
Reviewed
Bergeron, HC  (2023-11-03)
Created
Stephan, R  (2023-03-28)
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