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L mRNA is translated into protein L
Stable Identifier
R-HSA-9828719
Type
Reaction [omitted]
Species
Homo sapiens
Related Species
Human respiratory syncytial virus A
Compartment
cytosol
ReviewStatus
5/5
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Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
Respiratory syncytial virus (RSV) genome replication, transcription and translation (Homo sapiens)
Translation of respiratory syncytial virus mRNAs (Homo sapiens)
L mRNA is translated into protein L (Homo sapiens)
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
L mRNA of ~7.5 kb is translated into the L protein of ~200 kDa that serves as the catalytic subunit of the viral RNA-dependent RNA polymerase (RdRP) complex (Collins et al. 1984, Huang et al. 1985).
Literature References
PubMed ID
Title
Journal
Year
6546401
Identification of a tenth mRNA of respiratory syncytial virus and assignment of polypeptides to the 10 viral genes
Huang, YT
,
Wertz, GW
,
Collins, PL
J Virol
1984
3993233
Characterization of the 10 proteins of human respiratory syncytial virus: identification of a fourth envelope-associated protein
Huang, YT
,
Wertz, GW
,
Collins, PL
Virus Res
1985
Participants
Input
m7G(5')pppAm-capped,polyadenylated L mRNA [cytosol]
(Human respiratory syncytial virus A)
Output
Nascent L [cytosol]
(Human respiratory syncytial virus A)
Participates
as an event of
Translation of respiratory syncytial virus mRNAs (Homo sapiens)
Disease
Name
Identifier
Synonyms
respiratory syncytial virus infectious disease
DOID:1273
Authored
Orlic-Milacic, M (2023-02-16)
Reviewed
Bergeron, HC (2023-11-03)
Created
Orlic-Milacic, M (2023-02-16)
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