Expression of EPHA4 in presomitic mesoderm

Stable Identifier
R-HSA-9825582
Type
Reaction [uncertain]
Species
Homo sapiens
Compartment
nucleoplasm, plasma membrane
ReviewStatus
5/5
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Expression of EPHA4 in presomitic mesoderm
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EPHA4 is expressed in the rostral halves of somites (inferred from mouse embryos) where it appears to play a role in the determination of somite boundaries through interaction with an Ephrin on an adjacent cell (inferred from zebrafish embryos in Durbin et al. 1998, Barrios et al. 2003 and from chicken embryos in Glazier et al. 2008). Expression of EPHA4 is directly activated by MESP2, which shows the same expression pattern (inferred from mouse homologs).
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
MESP2:EPHA4 gene [nucleoplasm] (Homo sapiens)
Active Unit
MESP2 [nucleoplasm]
Inferred From
Expression of Epha4 in presomitic mesoderm (Mus musculus)
Authored
May, B  (2023-01-25)
Reviewed
Yamaguchi, TP  (2023-05-09)
Chalamalasetty, RB  (2023-05-09)
Created
May, B  (2023-01-26)
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