Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
pancreatic acinar cell
Stable Identifier
R-HSA-9820466
Type
Cell
Species
Homo sapiens
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Developmental Cell Lineages (Homo sapiens)
Developmental Cell Lineages of the Exocrine Pancreas (Homo sapiens)
Developmental Lineage of Pancreatic Acinar Cells (Homo sapiens)
Pancreatic pro-acinar cell produces pancreatic acinar cell (Homo sapiens)
pancreatic acinar cell (Homo sapiens)
Cytology
Organ
pancreas
(UBERON:0001264)
Tissue
exocrine pancreas
(UBERON:0000017)
Cell Type
pancreatic acinar cell
(CL:0002064)
Markers
Protein
SYCN [secretory granule membrane]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
PNLIPRP2 [zymogen granule]
(Homo sapiens)
Immunogenicity of SEREX-identified antigens and disease outcome in pancreatic cancer.
Cancer Immunol Immunother
59,
1389-400
(2010)
Heller, A., Zörnig, I., Müller, T., Giorgadze, K., Frei, C., Giese, T., Bergmann, F., Schmidt, J., Werner, J., Büchler, MW., Jaeger, D., Giese, NA.
GNMT [cytosol]
(Homo sapiens)
Tissue distribution of glycine N-methyltransferase, a major folate-binding protein of liver.
Proc Natl Acad Sci U S A
91,
210-4
(1994)
Yeo, EJ., Wagner, C.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
BHLHA15 [nucleoplasm]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
SPINK1 [zymogen granule]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
pro-CTRC [zymogen granule]
(Homo sapiens)
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
CEL [zymogen granule]
(Homo sapiens)
Abnormal exocrine-endocrine cell cross-talk promotes β-cell dysfunction and loss in MODY8.
Nat Metab
4,
76-89
(2022)
Kahraman, S., Dirice, E., Basile, G., Diegisser, D., Alam, J., Johansson, BB., Gupta, MK., Hu, J., Huang, L., Soh, CL., Huangfu, D., Muthuswamy, SK., Raeder, H., Molven, A., Kulkarni, RN.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
GATA4 [nucleoplasm]
(Homo sapiens)
The developmental transcription factor Gata4 is overexpressed in pancreatic ductal adenocarcinoma.
Int J Clin Exp Pathol
3,
47-55
(2009)
Karafin, MS., Cummings, CT., Fu, B., Iacobuzio-Donahue, CA.
Development of the human pancreas from foregut to endocrine commitment.
Diabetes
62,
3514-22
(2013)
Jennings, RE., Berry, AA., Kirkwood-Wilson, R., Roberts, NA., Hearn, T., Salisbury, RJ., Blaylock, J., Piper Hanley, K., Hanley, NA.
AMY2A [secretory granule lumen]
(Homo sapiens)
Pancreatic amylase expression in human pancreatic development.
Hybridoma
5,
137-45
(1986)
Davis, MM., Hodes, ME., Munsick, RA., Ulbright, TM., Goldstein, DJ.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
pro-CTRL [zymogen granule]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
SERPINA4 [zymogen granule]
(Homo sapiens)
Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands.
Histochem Cell Biol
110,
477-84
(1998)
Wolf, WC., Harley, RA., Sluce, D., Chao, L., Chao, J.
pro-PRSS1 [zymogen granule]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
pro-CPA2 [zymogen granule]
(Homo sapiens)
Novel Insights Into Immunohistochemical Analysis For Acinar Cell Neoplasm of The Pancreas: Carboxypeptidase A2, Carboxypeptidase A1, and Glycoprotein 2.
Am J Surg Pathol
47,
525-534
(2023)
Ishimoto-Namiki, U., Ino, Y., Esaki, M., Shimada, K., Saruta, M., Hiraoka, N.
pro-KLK1 [zymogen granule]
(Homo sapiens)
Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands.
Histochem Cell Biol
110,
477-84
(1998)
Wolf, WC., Harley, RA., Sluce, D., Chao, L., Chao, J.
proCELA2A [zymogen granule]
(Homo sapiens)
CELA2A mutations predispose to early-onset atherosclerosis and metabolic syndrome and affect plasma insulin and platelet activation.
Nat Genet
51,
1233-1243
(2019)
Esteghamat, F., Broughton, JS., Smith, E., Cardone, R., Tyagi, T., Guerra, M., Szabo, A., Ugwu, N., Mani, MV., Azari, B., Kayingo, G., Chung, S., Fathzadeh, M., Weiss, E., Bender, J., Mane, S., Lifton, RP., Adeniran, A., Nathanson, MH., Gorelick, FS., Hwa, J., Sahin-Tóth, M., Belfort-DeAguiar, R., Kibbey, RG., Mani, A.
PDIA2 [endoplasmic reticulum lumen]
(Homo sapiens)
Molecular characterization of a pancreas-specific protein disulfide isomerase, PDIp.
DNA Cell Biol
16,
269-74
(1997)
Desilva, MG., Notkins, AL., Lan, MS.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
REG1A [zymogen granule]
(Homo sapiens)
Expression of human regenerating gene mRNA and its product in normal and neoplastic human pancreas.
Cancer
70,
1857-63
(1992)
Kimura, N., Yonekura, H., Okamoto, H., Nagura, H.
Immunocytochemical localization of pancreatic stone protein in the human digestive tract.
Pancreas
1,
301-8
(1986)
Lechene de la Porte, P., de Caro, A., Lafont, H., Sarles, H.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
PTF1A [nucleoplasm]
(Homo sapiens)
Solid pseudopapillary neoplasms of the pancreas do not express major pancreatic markers in pediatric patients.
Hum Pathol
83,
29-35
(2019)
Calvani, J., Lopez, P., Sarnacki, S., Molina, TJ., Gibault, L., Fabre, M., Scharfmann, R., Capito, C., Galmiche, L.
pro-CPA1 [secretory granule lumen]
(Homo sapiens)
Novel Insights Into Immunohistochemical Analysis For Acinar Cell Neoplasm of The Pancreas: Carboxypeptidase A2, Carboxypeptidase A1, and Glycoprotein 2.
Am J Surg Pathol
47,
525-534
(2023)
Ishimoto-Namiki, U., Ino, Y., Esaki, M., Shimada, K., Saruta, M., Hiraoka, N.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester.
Stem Cells Transl Med
8,
1249-1264
(2019)
Villani, V., Thornton, ME., Zook, HN., Crook, CJ., Grubbs, BH., Orlando, G., De Filippo, R., Ku, HT., Perin, L.
Development of the human pancreas from foregut to endocrine commitment.
Diabetes
62,
3514-22
(2013)
Jennings, RE., Berry, AA., Kirkwood-Wilson, R., Roberts, NA., Hearn, T., Salisbury, RJ., Blaylock, J., Piper Hanley, K., Hanley, NA.
proCELA3B [zymogen granule]
(Homo sapiens)
CELA3B immunostaining is a highly specific marker for acinar cell carcinoma of the pancreas.
PLoS One
18,
e0287528
(2023)
Uhlig, R., Bröker, N., Weidemann, S., Gorbokon, N., Menz, A., Büscheck, F., Luebke, AM., Putri, D., Kluth, M., Hube-Magg, C., Hinsch, A., Lennartz, M., Reiswich, V., Höflmayer, D., Fraune, C., Möller, K., Bernreuther, C., Lebok, P., Sauter, G., Minner, S., Steurer, S., Burandt, E., Krech, R., Dum, D., Marx, A., Simon, R., Krech, T., Clauditz, TS., Jacobsen, F.
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
PNLIP [zymogen granule]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
AQP8 [plasma membrane]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
Distribution of aquaporin water channels AQP1 and AQP5 in the ductal system of the human pancreas.
Gut
52,
1008-16
(2003)
Burghardt, B., Elkaer, ML., Kwon, TH., Rácz, GZ., Varga, G., Steward, MC., Nielsen, S.
RNASE1 [zymogen granule]
(Homo sapiens)
Human pancreatic ribonuclease 1: expression and distribution in pancreatic adenocarcinoma.
Cancer
89,
1252-8
(2000)
Peracaula, R., Cleary, KR., Lorenzo, J., de Llorens, R., Frazier, ML.
GP2 [plasma membrane]
(Homo sapiens)
pro-CPB1 [zymogen granule]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
pro-PLA2G1B [zymogen granule]
(Homo sapiens)
The human pancreas proteome defined by transcriptomics and antibody-based profiling.
PLoS One
9,
e115421
(2014)
Danielsson, A., Pontén, F., Fagerberg, L., Hallström, BM., Schwenk, JM., Uhlén, M., Korsgren, O., Lindskog, C.
RNA
PLA2G1B mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
REG1B mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CELA3A mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
ANPEP mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
AQP8 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CELA3B mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CTRB1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
SGK1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
REG3A mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PDIA2 mRNA [cytosol]
(Homo sapiens)
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
RBPJL mRNA [cytosol]
(Homo sapiens)
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
KLK1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
FGL1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
GATA4 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
SERPINI2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CPB1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
REG1A mRNA [cytosol]
(Homo sapiens)
Expression of human regenerating gene mRNA and its product in normal and neoplastic human pancreas.
Cancer
70,
1857-63
(1992)
Kimura, N., Yonekura, H., Okamoto, H., Nagura, H.
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CPA2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
AMY2B mRNA [cytosol]
(Homo sapiens)
Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells.
Stem Cell Reports
8,
1675-1688
(2017)
Trott, J., Tan, EK., Ong, S., Titmarsh, DM., Denil, SLIJ., Giam, M., Wong, CK., Wang, J., Shboul, M., Eio, M., Cooper-White, J., Cool, SM., Rancati, G., Stanton, LW., Reversade, B., Dunn, NR.
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CPA1 mRNA [cytosol]
(Homo sapiens)
Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells.
Stem Cell Reports
8,
1675-1688
(2017)
Trott, J., Tan, EK., Ong, S., Titmarsh, DM., Denil, SLIJ., Giam, M., Wong, CK., Wang, J., Shboul, M., Eio, M., Cooper-White, J., Cool, SM., Rancati, G., Stanton, LW., Reversade, B., Dunn, NR.
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel.
Pancreas
49,
983-998
(2020)
Ellison, MA., Spagnolo, DM., Shelton, C., Orlova, E., LaRusch, J., Whitcomb, DC., Haupt, M.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
Single-cell transcriptomic and spatial landscapes of the developing human pancreas.
Cell Metab
35,
184-199.e5
(2023)
Olaniru, OE., Kadolsky, U., Kannambath, S., Vaikkinen, H., Fung, K., Dhami, P., Persaud, SJ.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester.
Stem Cells Transl Med
8,
1249-1264
(2019)
Villani, V., Thornton, ME., Zook, HN., Crook, CJ., Grubbs, BH., Orlando, G., De Filippo, R., Ku, HT., Perin, L.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
REG3G mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PTF1A mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
LYZ mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
SDC4 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
AMY2A mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
LDHB mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
GP2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester.
Stem Cells Transl Med
8,
1249-1264
(2019)
Villani, V., Thornton, ME., Zook, HN., Crook, CJ., Grubbs, BH., Orlando, G., De Filippo, R., Ku, HT., Perin, L.
PRSS2 mRNA [cytosol]
(Homo sapiens)
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
SERPINA4 mRNA [cytosol]
(Homo sapiens)
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PRSS3 mRNA [cytosol]
(Homo sapiens)
Long-Term Culture of Self-renewing Pancreatic Progenitors Derived from Human Pluripotent Stem Cells.
Stem Cell Reports
8,
1675-1688
(2017)
Trott, J., Tan, EK., Ong, S., Titmarsh, DM., Denil, SLIJ., Giam, M., Wong, CK., Wang, J., Shboul, M., Eio, M., Cooper-White, J., Cool, SM., Rancati, G., Stanton, LW., Reversade, B., Dunn, NR.
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CELA2A mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
BHLHA15 mRNA [cytosol]
(Homo sapiens)
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
CTRB2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PRSS1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel.
Pancreas
49,
983-998
(2020)
Ellison, MA., Spagnolo, DM., Shelton, C., Orlova, E., LaRusch, J., Whitcomb, DC., Haupt, M.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Single-cell transcriptomic and spatial landscapes of the developing human pancreas.
Cell Metab
35,
184-199.e5
(2023)
Olaniru, OE., Kadolsky, U., Kannambath, S., Vaikkinen, H., Fung, K., Dhami, P., Persaud, SJ.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
IGFBP1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
RNASE1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CTRC mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel.
Pancreas
49,
983-998
(2020)
Ellison, MA., Spagnolo, DM., Shelton, C., Orlova, E., LaRusch, J., Whitcomb, DC., Haupt, M.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
TMEM97 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
SPINK1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel.
Pancreas
49,
983-998
(2020)
Ellison, MA., Spagnolo, DM., Shelton, C., Orlova, E., LaRusch, J., Whitcomb, DC., Haupt, M.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Single-cell transcriptomic and spatial landscapes of the developing human pancreas.
Cell Metab
35,
184-199.e5
(2023)
Olaniru, OE., Kadolsky, U., Kannambath, S., Vaikkinen, H., Fung, K., Dhami, P., Persaud, SJ.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CEL mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Complex Genetics in Pancreatitis: Insights Gained From a New Candidate Locus Panel.
Pancreas
49,
983-998
(2020)
Ellison, MA., Spagnolo, DM., Shelton, C., Orlova, E., LaRusch, J., Whitcomb, DC., Haupt, M.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
The expression of the carboxyl ester lipase gene in pancreas and pancreatic adenocarcinomas.
Int J Oncol
29,
649-54
(2006)
Reuss, R., Aberle, S., Klingel, K., Sauter, M., Greschniok, A., Franke, FE., Padberg, W., Blin, N.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CLPS mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PNLIP mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Transcriptional Profile of Human Pancreatic Acinar Ductal Metaplasia.
Gastro Hep Adv
2,
532-543
(2023)
Jiang, J., Hakimjavadi, H., Bray, JK., Perkins, C., Gosling, A., daSilva, L., Bulut, G., Ali, J., Setiawan, VW., Campbell-Thompson, M., Chamala, S., Schmittgen, TD.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
CTRL mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
LGALS2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PNLIPRP1 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PNLIPRP2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
PRSS3P2 mRNA [cytosol]
(Homo sapiens)
A Single-Cell Transcriptome Atlas of the Human Pancreas.
Cell Syst
3,
385-394.e3
(2016)
Muraro, MJ., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, MA., Carlotti, F., de Koning, EJ., van Oudenaarden, A.
Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes.
Cell Metab
24,
593-607
(2016)
Segerstolpe, Å., Palasantza, A., Eliasson, P., Andersson, EM., Andréasson, AC., Sun, X., Picelli, S., Sabirsh, A., Clausen, M., Bjursell, MK., Smith, DM., Kasper, M., Ämmälä, C., Sandberg, R.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
SYCN mRNA [cytosol]
(Homo sapiens)
Single-cell transcriptomes identify human islet cell signatures and reveal cell-type-specific expression changes in type 2 diabetes.
Genome Res
27,
208-222
(2017)
Lawlor, N., George, J., Bolisetty, M., Kursawe, R., Sun, L., Sivakamasundari, V., Kycia, I., Robson, P., Stitzel, ML.
Adult human pancreatic acinar cells dedifferentiate into an embryonic progenitor-like state in 3D suspension culture.
Sci Rep
9,
4040
(2019)
Baldan, J., Houbracken, I., Rooman, I., Bouwens, L.
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage.
Cell Metab
35,
1944-1960.e7
(2023)
Doke, M., Álvarez-Cubela, S., Klein, D., Altilio, I., Schulz, J., Mateus Gonçalves, L., Almaça, J., Fraker, CA., Pugliese, A., Ricordi, C., Qadir, MMF., Pastori, RL., Domínguez-Bendala, J.
Single-cell transcriptomes reveal characteristic features of human pancreatic islet cell types.
EMBO Rep
17,
178-87
(2016)
Li, J., Klughammer, J., Farlik, M., Penz, T., Spittler, A., Barbieux, C., Berishvili, E., Bock, C., Kubicek, S.
Participates
as an output of
Pancreatic pro-acinar cell produces pancreatic acinar cell (Homo sapiens)
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text