ST6GALNAC2 transfers sialic acid to Core 1 mucins

Stable Identifier
R-HSA-981814
Type
Reaction [transition]
Species
Homo sapiens
Compartment
Golgi lumen, Golgi membrane
Synonyms
GalNAc alpha-2,6-sialyltransferase II can add a sialic acid to the T antigen at the alpha 6 position
ReviewStatus
5/5
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ST6GALNAC2 transfers sialic acid to Core 1 mucins
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The huma gene ST6GALNAC2 encodes GalNAc alpha-2,6-sialyltransferase II which mediates the transfer of sialic acid (Neu5Ac) onto the T antigen (Samyn-Petit et al. 2000).
Literature References
PubMed ID Title Journal Year
10742600 Molecular cloning and functional expression of human ST6GalNAc II. Molecular expression in various human cultured cells

Harduin-Lepers, A, Delannoy, P, Samyn-Petit, B, Krzewinski-Recchi, MA, Steelant, WF

Biochim Biophys Acta 2000
Participants
Input
Output
Participates
as an event of
Catalyst Activity

sialyltransferase activity of ST6GALNAC2 [Golgi membrane]

Physical Entity
ST6GALNAC2 [Golgi membrane] (Homo sapiens)
Activity
sialyltransferase activity (GO:0008373)
Orthologous Events
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Bos taurus)
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Canis familiaris)
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Gallus gallus)
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Mus musculus)
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Rattus norvegicus)
ST6GALNAC2 transfers sialic acid to Core 1 mucins (Sus scrofa)
Authored
Jassal, B  (2010-10-15)
Reviewed
Ferrer, A  (2011-11-04)
Created
Jassal, B  (2010-10-27)
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