AcK-NFE2L2 binds the PDGFA gene

Stable Identifier
R-HSA-9796069
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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AcK-NFE2L2 binds the PDGFA gene
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NFE2L2 binding to the PDGFA promoter and recruits SP1 on it to facilitate PDGFA expression. (Liu et al, 2016))
Literature References
PubMed ID Title Journal Year
27588483 Activation of AKT pathway by Nrf2/PDGFA feedback loop contributes to HCC progression

Liu, G, Zeng, W, Liu, Y, Zhang, Y, Zhang, N, Wei, Y, Liu, D, Zou, L, Gao, Q

Oncotarget 2016
Participants
Input
Output
Participates
as an event of
This event is regulated
Positively by
Regulator
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm] (Homo sapiens)
Active Unit
p-S,T-NFE2L2 [nucleoplasm]
Regulator
MAFK [nucleoplasm] (Homo sapiens)
Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-08-04)
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