AcK-NFE2L2 binds the ABCC3 gene

Stable Identifier
R-HSA-9796065
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
AcK-NFE2L2 binds the ABCC3 gene
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
ABCC3 is under transcriptional control of NFE2L2 and contains a functional antioxidant response element within the eighth intron of the human ABCC3 gene. The same has been confirmed through ChIP and Pull-down assay (Canet et al, 2015; Pellegatta et al, 2019)

Literature References
PubMed ID Title Journal Year
25349122 Identification of a functional antioxidant response element within the eighth intron of the human ABCC3 gene

Canet, MJ, Merrell, MD, Harder, BG, Maher, JM, Wu, T, Lickteig, AJ, Jackson, JP, Zhang, DD, Yamamoto, M, Cherrington, NJ

Drug Metab Dispos 2015
31771235 ABCC3 Expressed by CD56dim CD16+ NK Cells Predicts Response in Glioblastoma Patients Treated with Combined Chemotherapy and Dendritic Cell Immunotherapy

Pellegatta, S, Di Ianni, N, Pessina, S, Paterra, R, Anghileri, E, Eoli, M, Finocchiaro, G

Int J Mol Sci 2019
Participants
Input
Output
Participates
as an event of
Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-08-04)
Cite Us!