NFE2L2 regulating MDR associated enzymes

Stable Identifier
R-HSA-9818032
Type
Pathway
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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NFE2L2 regulating MDR associated enzymes
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Subpathway representing multi-drug resistance (MDR) gene regulated by NFE2L2 (NRF2). These MDR-related genes are known to play a role in Drug resistance. For example, ABCF2 have a role in Cisplatin resistance in ovarian cancer (Bao et al, 2017). Similarly ABCC1 (MRP1), ABCC3 and ABCG2 also have a role in multiple drug resistance (Cole et al,2014; Zeng et al,1999; Mo et al, 2012).
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Authored
Tiwari, K  (2023-08-08)
Created
Tiwari, K  (2022-10-10)
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