SRF binds NPAS4 gene promoter

Stable Identifier
R-HSA-9768832
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
SRF binds NPAS4 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Based on studies in mouse, SRF (Serum response factor) binds to the promoter region of the NPAS4 gene upon neuronal excitation (Kuzniewska et al. 2016), when Srf accumulation and phosphorylation are observed (Morris et al. 1999, Herdegen et al. 1997). Two SRF binding sites are highly conserved between human and mouse NPAS4 gene promoters (Kuzniewska et al. 2016).
Participants
Input
Output
Participates
as an event of
Inferred From
Srf binds Npas4 gene promoter (Mus musculus)
Authored
Orlic-Milacic, M  (2022-04-08)
Reviewed
Lin, Y  (2022-07-29)
Created
Orlic-Milacic, M  (2022-03-14)
Cite Us!