ZEB1 recruits SETD8 to CDH1 gene promoter

Stable Identifier
R-HSA-9765791
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, nucleoplasm
ReviewStatus
3/5
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ZEB1 recruits SETD8 to CDH1 gene promoter
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SETD8 is recruited to the CDH1 gene promoter in a ZEB1-dependent manner to repress CDH1 gene transcription (Hou et al. 2015).
Literature References
PubMed ID Title Journal Year
26717907 SET8 induces epithelial‑mesenchymal transition and enhances prostate cancer cell metastasis by cooperating with ZEB1

Hou, L, Li, Q, Yu, Y, Li, M, Zhang, D

Mol Med Rep 2016
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Orthologous Events
ZEB1 recruits SETD8 to CDH1 gene promoter (Bos taurus)
ZEB1 recruits SETD8 to CDH1 gene promoter (Caenorhabditis elegans)
ZEB1 recruits SETD8 to CDH1 gene promoter (Danio rerio)
ZEB1 recruits SETD8 to CDH1 gene promoter (Drosophila melanogaster)
ZEB1 recruits SETD8 to CDH1 gene promoter (Gallus gallus)
ZEB1 recruits SETD8 to CDH1 gene promoter (Mus musculus)
ZEB1 recruits SETD8 to CDH1 gene promoter (Rattus norvegicus)
ZEB1 recruits SETD8 to CDH1 gene promoter (Sus scrofa)
ZEB1 recruits SETD8 to CDH1 gene promoter (Xenopus tropicalis)
Authored
Orlic-Milacic, M  (2022-02-16)
Created
Orlic-Milacic, M  (2022-02-16)
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