TWIST1 recruits SETD8 to CDH1 gene promoter

Stable Identifier
R-HSA-9765788
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
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TWIST1 recruits SETD8 to CDH1 gene promoter
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TWIST1 can recruit SETD8 (SET8) histone methyltransferase to the CDH1 gene promoter, which enhances repression of CDH1 gene transcription (Yang et al. 2012).
Literature References
PubMed ID Title Journal Year
21983900 SET8 promotes epithelial-mesenchymal transition and confers TWIST dual transcriptional activities

Yang, F, Sun, L, Li, Q, Han, X, Lei, L, Zhang, H, Shang, Y

EMBO J 2012
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Orthologous Events
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TWIST1 recruits SETD8 to CDH1 gene promoter (Drosophila melanogaster)
TWIST1 recruits SETD8 to CDH1 gene promoter (Gallus gallus)
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TWIST1 recruits SETD8 to CDH1 gene promoter (Rattus norvegicus)
TWIST1 recruits SETD8 to CDH1 gene promoter (Sus scrofa)
Authored
Orlic-Milacic, M  (2022-02-16)
Created
Orlic-Milacic, M  (2022-02-16)
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