FOXA2 binds CDH1 gene promoter

Stable Identifier
R-HSA-9765371
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
3/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
FOXA2 binds CDH1 gene promoter
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
FOXA2 binds to the CDH1 gene promoter by chromatin immunoprecipitation (ChIP) (Zhang et al. 2015, Bow et al. 2020). FOXA2 may recruit its interaction partner FOXP2 to the CDH1 gene promoter (Liu et al. 2021).
Literature References
PubMed ID Title Journal Year
25779673 FOXA2 attenuates the epithelial to mesenchymal transition by regulating the transcription of E-cadherin and ZEB2 in human breast cancer

Zhang, Z, Yang, C, Gao, W, Chen, T, Qian, T, Hu, J, Tan, Y

Cancer Lett 2015
31957176 Silencing of FOXA2 decreases E-cadherin expression and is associated with lymph node metastasis in oral cancer

Bow, YD, Wang, YY, Chen, YK, Su, CW, Hsu, CW, Xiao, LY, Yuan, SS, Li, RN

Oral Dis 2020
Participants
Input
Output
Participates
as an event of
Authored
Orlic-Milacic, M  (2022-02-15)
Created
Orlic-Milacic, M  (2022-02-15)
Cite Us!