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Expression of SNAI1 during gastrulation
Stable Identifier
R-HSA-9756439
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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Developmental Biology (Homo sapiens)
Gastrulation (Homo sapiens)
Epithelial-Mesenchymal Transition (EMT) during gastrulation (Homo sapiens)
Expression of SNAI1 during gastrulation (Homo sapiens)
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The Snail1 (SNAI1) gene is transcribed to yield mRNA and the mRNA is translated to yield SNAI1 protein. Transcription of SNAI1 is activated by EOMES and TBXT (inferred from mouse homologs) and by FGF signaling via FGFR1 (inferred from mouse homologs).
Participants
Input
SNAI1 gene [nucleoplasm]
(Homo sapiens)
Output
SNAI1 [nucleoplasm]
(Homo sapiens)
Participates
as an event of
Epithelial-Mesenchymal Transition (EMT) during gastrulation (Homo sapiens)
This event is regulated
Positively by
Regulator
FGFR1 [plasma membrane]
(Homo sapiens)
Regulator
EOMES:TBXT:SNAI1 gene [nucleoplasm]
(Homo sapiens)
Inferred From
Expression of Snai1 during gastrulation (Mus musculus)
Authored
May, B (2021-10-10)
Reviewed
Probst, S (2022-07-18)
Zissel, L (2022-07-18)
Created
May, B (2021-10-14)
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